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desbutylbenflumetol

Known as: desbutyl benflumetol, desbutyl-benflumetol 
National Institutes of Health

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2 relations

Broader (2)

EthanolaminesFluorenes

Papers overview

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2015
2015
A fast and sensitive method for quantifying lumefantrine and desbutyl-lumefantrine using LC-MS/MS.
2012
2012
Gender differences in pharmacokinetics of lumefantrine and its metabolite desbutyl-lumefantrine in rats.
Lumefantrine has been reported to be mainly bio-transformed by cytochrome P450 isozyme 3A4 to desbutyl-lumefantrine (DLF) in… 
Highly Cited
2011
Highly Cited
2011
Population Pharmacokinetics of Artemether, Lumefantrine, and Their Respective Metabolites in Papua New Guinean Children with Uncomplicated Malaria
ABSTRACT There are sparse published data relating to the pharmacokinetic properties of artemether, lumefantrine, and their active… 
2011
2011
Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection.
2008
2008
Interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum in vitro
ZusammenfassungDie pharmakodynamische Interaktion zwischen Lumefantrin und seinem Monodesbutyl-Analog (DBB) wurde bei 35 frischen… 
2007
2007
Specific pharmacokinetic interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum
ZusammenfassungDie blutschizontozide Wirkung von Lumefantrin, Monodesbutyl-Benflumetol und einer 999:1 Kombination beider… 
2007
2007
Synergistic interaction between monodesbutyl-benflumetol and retinol in Plasmodium falciparum
ZusammenfassungDie blutschizontozide Wirkung von Monodesbutyl-Benflumetol (DBB), Retinol (RET) und Kombinationen beider… 
2005
2005
Synergism of desbutyl-benflumetol and retinol against Plasmodium falciparum in vitro
SummaryThis in vitro study was conducted to assess the blood schizontocidal activity of desbutyl-benflumetol (DBB), a new… 
2004
2004
Comparative study on the in vitro activity of lumefantrine and desbutyl-benflumetol in fresh isolates of Plasmodium vivax from Thailand.
The occurrence of chloroquine resistance in Plasmodium vivax underlines the need for monitoring the drug response of this… 
2001
2001
Desbutyl-Benflumetol, a Novel Antimalarial Compound: In Vitro Activity in Fresh Isolates of Plasmodium falciparumfrom Thailand
ABSTRACT Desbutyl-benflumetol (DBB) is a novel antimalarial compound closely related to benflumetol (lumefantrine), of which it… 
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