FAQ

deoxyribonuclease II activity

Known as: acid DNase activity, DNase II activity, deoxyribonucleate 3'-nucleotidohydrolase activity 
Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products. [EC:3.1.22.1]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
02419562016

Papers overview

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2013
2013
Melatonin protects rat thymus against oxidative stress caused by exposure to microwaves and modulates proliferation/apoptosis of thymocytes.
The aim of the study was to evaluate the effect of melatonin on oxidative stress, DNA fragmentation, apoptsis and proliferation… (More)
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2012
2012
Genetic and expression analysis of SNPs in the human deoxyribonuclease II: SNPs in the promoter region reduce its in vivo activity through decreased promoter activity.
Five SNPs in the human DNase II gene have been reported to be associated with rheumatoid arthritis (RA). Genotype and haplotype… (More)
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2010
2010
Cytomixis-like chromosomes/chromatin elimination from pollen mother cells (PMCs) in wheat-rye allopolyploids
Polyploidy is an important event and major force in plant speciation. Amongst the polyploids, allopolyploids have attracted… (More)
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2006
2006
DNase II deficiency impairs innate immune function in Drosophila.
DNase II enzymes are highly conserved proteins that are required for the degradation of DNA within phagolysosomes. Engulfment of… (More)
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2004
2004
The LEI/L-DNase II pathway is activated in light-induced retinal degeneration in rats.
Retinal death induced by light seems to be a caspase-independent process. In this work we investigate the LEI/L-DNase II pathway… (More)
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2003
2003
L-DNase II activation by the 24 kDa apoptotic protease (AP24) in TNFα-induced apoptosis
The 24 kDa apoptotic protease (AP24) is a serine protease with elastase-like activity that is activated during TNFaor UV light… (More)
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2000
2000
Nuclear translocation of a leukocyte elastase Inhibitor/Elastase complex during staurosporine-induced apoptosis: role in the generation of nuclear L-DNase II activity.
Using L1210 murine leukemia cells, we have previously shown that in response to treatment with drugs having different targets… (More)
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1995
1995
Deoxyribonuclease II (DNase II) activity in mouse tissues and body fluids.
The distribution of deoxyribonuclease II (DNase II) in tissues and body fluids was examined in 12-week-old C3H/He mice. Activity… (More)
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1992
1992
Genetic polymorphism of human deoxyribonuclease II (DNase II): low activity levels in urine and leukocytes are due to an autosomal recessive allele.
The objectives of this study were to elucidate the genetic basis of human deoxyribonuclease II (DNase II) and to evaluate its… (More)
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1985
1985
The subunit structure and active site sequence of porcine spleen deoxyribonuclease.
An acid DNase (DNase II) from porcine spleen was purified by sequential chromatography over carboxymethyl-cellulose, blue dextran… (More)
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