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dendritic spine maintenance

The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The epilepsy and intellectual disability-associated protein TBC1D24 regulates the maintenance of excitatory synapses and animal behaviors
Perturbation of synapse development underlies many inherited neurodevelopmental disorders including intellectual disability (ID… Expand
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2018
2018
Pin1 mediates Aβ42-induced dendritic spine loss
Calcineurin inhibitors may prevent amyloid-induced progression of Alzheimer’s disease by preventing suppression of the isomerase… Expand
2016
2016
Maternal Loss of Ube3a Impairs Experience-Driven Dendritic Spine Maintenance in the Developing Visual Cortex
Dendritic spines are a morphological feature of the majority of excitatory synapses in the mammalian neocortex and are motile… Expand
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2016
2016
The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines
Dendritic spine stabilization depends on afferent synaptic input and requires changes in actin cytoskeleton dynamics and protein… Expand
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Review
2014
Review
2014
The Potential Role of Rho GTPases in Alzheimer's Disease Pathogenesis
Alzheimer's disease (AD) is characterized by a wide loss of synapses and dendritic spines. Despite extensive efforts, the… Expand
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2013
2013
Decreased dendritic spine density as a consequence of tetanus toxin light chain expression in single neurons in vivo
Tetanus toxin light chain has been used for some time as a genetically-encoded tool to inhibit neurotransmission and thereby… Expand
2012
2012
Regulation of hippocampal long‐term potentiation and long‐term depression by diacylglycerol kinaseζ
Diacylglycerol (DAG) is an important signaling molecule at neuronal synapses. Generation of synaptic DAG is triggered by the… Expand
2012
2012
Abnormalities of the Duo/Ras-Related C3 Botulinum Toxin Substrate 1/p21-Activated Kinase 1 Pathway Drive Myosin Light Chain Phosphorylation in Frontal Cortex in Schizophrenia
BACKGROUND Recent studies on GTPases have suggested that reduced Duo and cell division cycle 42 (Cdc42) transcript expression is… Expand
Highly Cited
2009
Highly Cited
2009
Synaptic removal of diacylglycerol by DGKζ and PSD‐95 regulates dendritic spine maintenance
Diacylglycerol (DAG) is an important lipid signalling molecule that exerts an effect on various effector proteins including… Expand
2008
2008
The RhoA‐associated protein Citron‐N controls dendritic spine maintenance by interacting with spine‐associated Golgi compartments
Dendritic spines are highly dynamic protuberances that are thought to be crucial for learning and memory. Although it is well… Expand
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