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del(17p13)

Known as: -17p13, 17p13 Deletion, Del(17)(p13) 
A deletion of chromosomal material at 17p13. This chromosomal aberration includes deletion of the TP53 gene and is associated with multiple myeloma… 
National Institutes of Health

Related topics

Related topics

17 relations

Broader (1)

17p13
Aleukemic Chronic Lymphocytic LeukemiaChromosomes, Human, Pair 17Chronic Lymphocytic Leukemia with Plasmacytoid DifferentiationChronic Lymphocytic Leukemia with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene

Papers overview

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Highly Cited
2012
Highly Cited
2012
Monoclonal B‐cell lymphocytosis is closely related to chronic lymphocytic leukaemia and may be better classified as early‐stage CLL
The World Health Organization classification uses a cut‐off point of 5·0 × 109/l cells with a chronic lymphocytic leukaemia (CLL… 
Highly Cited
2012
Highly Cited
2012
Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations
Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults in Western countries. Chromosomal abnormalities… 
Highly Cited
2011
Highly Cited
2011
Chromosomal aberrations +1q21 and del(17p13) predict survival in patients with recurrent multiple myeloma treated with lenalidomide and dexamethasone
In the era of novel agents such as lenalidomide and bortezomib, risk stratification by chromosomal abnormalities may enable a… 
Highly Cited
2010
Highly Cited
2010
Gain of 1q21 is an unfavorable genetic prognostic factor for multiple myeloma patients treated with high-dose chemotherapy.
Highly Cited
2009
Highly Cited
2009
Influence of cytogenetics in patients with relapsed or refractory multiple myeloma treated with lenalidomide plus dexamethasone: adverse effect of deletion 17p13.
Although the combination of lenalidomide and dexamethasone is effective therapy for patients with relapsed/refractory multiple… 
Review
2009
Review
2009
Richter syndrome: molecular insights and clinical perspectives
Richter syndrome (RS) represents the clinico‐pathologic transformation of chronic lymphocytic leukaemia (CLL) to an aggressive… 
Highly Cited
2009
Highly Cited
2009
A new microduplication syndrome encompassing the region of the Miller–Dieker (17p13 deletion) syndrome
Background: The use of array comparative genome hybridisation (CGH) analyses for investigation of children with mental… 
2005
2005
Interneuron deficits in patients with the Miller-Dieker syndrome
Lissencephaly is characterized by a thickened cortex and loss of gyri, resulting in the brain having a smooth surface. Patients… 
Highly Cited
2002
Highly Cited
2002
Late appearance of the 11q22.3-23.1 deletion involving the ATM locus in B-cell chronic lymphocytic leukemia and related disorders. Clinico-biological significance.
BACKGROUND AND OBJECTIVES Chromosome 11q22.3-23.1 deletions involving the ataxia-teleangiectasia mutated (ATM) locus (11q-/ATM… 
Highly Cited
2001
Highly Cited
2001
Allelic loss and gain, but not genomic instability, as the major somatic mutation in primary hepatocellular carcinoma
To identify genetic abnormalities in primary hepatocellular carcinoma (HCC), we performed microsatellite analysis (MSA) on 60… 
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