del(17p13)

Known as: -17p13, 17p13 Deletion, Del(17)(p13) 
A deletion of chromosomal material at 17p13. This chromosomal aberration includes deletion of the TP53 gene and is associated with multiple myeloma… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
PURPOSE The aim of this study was to analyze chromosomal aberrations in terms of frequency and impact on time to progression in… (More)
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Highly Cited
2012
Highly Cited
2012
In patients with multiple myeloma (MM), risk stratification by chromosomal abnormalities may enable a more rational selection of… (More)
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Highly Cited
2012
Highly Cited
2012
The association of genetic lesions detected by fluorescence in situ hybridization (FISH) with survival was analyzed in 1069… (More)
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2011
2011
BACKGROUND In the era of novel agents such as lenalidomide and bortezomib, risk stratification by chromosomal abnormalities may… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Chromosomal abnormalities have been shown to play a major role in disease evolution of multiple myeloma. Specific… (More)
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2010
2010
The poor prognosis of chronic lymphocytic leukemia (CLL) patients with del(17p13) is well established. Several studies have shown… (More)
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Highly Cited
2009
Highly Cited
2009
Although the combination of lenalidomide and dexamethasone is effective therapy for patients with relapsed/refractory multiple… (More)
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Highly Cited
2009
Highly Cited
2009
We previously reported interim results of a phase 1 trial in patients with chronic lymphocytic leukemia (CLL) whereby… (More)
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Highly Cited
2007
Highly Cited
2007
In chronic lymphocytic leukemia (CLL), the acquisition of new genomic aberrations during the disease course (clonal evolution) is… (More)
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Highly Cited
2005
Highly Cited
2005
Fluorescence in situ hybridization (FISH) is more sensitive than conventional cytogenetics for recognizing chromosomal changes… (More)
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