degrasyn

Known as: 2-cyano-N-(1-phenylbutyl)-3-(6-bromopyridin-2-yl)acrylamide, WP1130 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2018
024620072018

Papers overview

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2015
2015
Antiestrogen resistance is a major problem in breast cancer treatment. Therefore, the search for new therapeutic targets and… (More)
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2015
2015
Autophagy represents an intracellular degradation process which is involved in both regular cell homeostasis and disease settings… (More)
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2014
2014
The transcription factor E-twenty-six related gene (ERG), which is overexpressed through gene fusion with the androgen-responsive… (More)
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2012
2012
It has been shown in many solid tumors that the overexpression of the pro-survival Bcl-2 family members Bcl-xL and Mcl-1 confers… (More)
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2012
2012
Ubiquitin (Ub) is a vital regulatory component in various cellular processes, including cellular responses to viral infection. As… (More)
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2011
2011
Although chronic myelogenous leukemia (CML) is effectively controlled by Bcr-Abl kinase inhibitors, resistance to inhibitors… (More)
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2011
2011
AG490 is a tyrosine kinase inhibitor with activity against Jak2 and apoptotic activity in specific leukemias. Due to its weak… (More)
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Highly Cited
2010
Highly Cited
2010
Recent evidence suggests that several deubiquitinases (DUB) are overexpressed or activated in tumor cells and many contribute to… (More)
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2010
2010
Mantle cell lymphoma (MCL) is an aggressive histotype of B-cell non-Hodgkin lymphoma that has increased in incidence over the… (More)
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2007
2007
c-Myc is a highly unstable transcription factor whose deregulation and increased expression are associated with cancer. Degrasyn… (More)
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