degradosome
National Institutes of Health
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Polynucleotide phosphorylase (PNPase) is a 3′–5′-exoribnuclease that is found in most bacteria and in some eukaryotic organelles…
My entry into the RNA world began in 1967 when a visiting lecturer at the University of Toronto, the late Dr. Gordon Tener…
RNase E of Escherichia coli is a membrane-associated endoribonuclease that has a major role in mRNA degradation. The enzyme has a…
Yersinia polynucleotide phosphorylase (PNPase), a 3'-5' exoribonuclease, has been shown to affect growth during several stress…
The RNA degradosome is built on the C‐terminal half of ribonuclease E (RNase E) which shows high sequence variation, even amongst…
The RNA degradosome of Escherichia coli is a multiprotein complex that plays an essential role in normal RNA processing and decay…
The exosome is a protein complex consisting of a variety of 3′→5′ exoribonucleases that functions both in the processing of rRNA…
ABSTRACT RNase E, the principal RNase capable of initiating mRNA decay, preferentially attacks 5′-monophosphorylated over 5…
Recently, we found that a multicomponent ribonucleolytic degradosome complex formed around RNase E, a key mRNA-degrading and 9S…