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decidium

National Institutes of Health

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Phenanthridines

Papers overview

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2005
2005
Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE.
Highly Cited
2003
Highly Cited
2003
Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
The peripheral anionic site on acetylcholinesterase (AChE), located at the active center gorge entry, encompasses overlapping… 
1992
1992
Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase.
This paper examines inhibition of acetylcholinesterase (AchE) and butyrylcholinesterase (BuchE) by tetrahydroaminoacridine (THA… 
1989
1989
Chiral nature of covalent methylphosphonyl conjugates of acetylcholinesterase.
This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with… 
1987
1987
Site selectivity of fluorescent bisquaternary phenanthridinium ligands for acetylcholinesterase.
The synthesis of decidium and hexidium diiodides, their spectroscopic properties, and association with acetylcholinesterase from… 
1987
1987
Decidium. A novel fluorescent probe of the agonist/antagonist and noncompetitive inhibitor sites on the nicotinic acetylcholine receptor.
1986
1986
Kinetic, equilibrium, and spectroscopic studies on dealkylation ("aging") of alkyl organophosphonyl acetylcholinesterase. Electrostatic control of enzyme topography.
1986
1986
Kinetic, equilibrium and spectroscopic studies on cation association at the active center of acetylcholinesterase: topographic distinction between trimethyl and trimethylammonium sites.
1985
1985
Spatial Relationships between Drug Binding Sites on the Surface of the Acetylcholine Receptor: Preparation and Interaction of Fluorescent Alpha-Toxins and Decidium with the Acetylcholine Receptor
Abstract : This report described the development of fluorescent probes of the nicotinic acetylcholine receptor and their use in… 
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