decapentaplegic signaling pathway

Known as: dpp signaling pathway 
A series of molecular signals initiated by the binding of decapentaplegic (dpp) to a receptor on the surface of a target cell, and ending with… (More)
National Institutes of Health

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negative regulation of decapentaplegic signaling pathway

Papers overview

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2019
2019
(+)-Isobicyclogermacrenal and spathulenol from Aristolochia yunnanensis alleviate cardiac fibrosis by inhibiting transforming growth factor β/small mother against decapentaplegic signaling pathway.
Cardiac fibrosis contributes to both systolic and diastolic dysfunction in many cardiac pathophysiologic conditions. Antifibrotic… (More)
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2016
2016
Target genes of Dpp/BMP signaling pathway revealed by transcriptome profiling in the early D.melanogaster embryo.
In the early Drosophila melanogaster embryo, the gene regulatory network controlled by Dpp signaling is involved in the… (More)
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2013
2013
optix functions as a link between the retinal determination network and the dpp pathway to control morphogenetic furrow progression in Drosophila.
optix, the Drosophila ortholog of the SIX3/6 gene family in vertebrate, encodes a homeodomain protein with a SIX protein-protein… (More)
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2012
2012
Developmental role of dpp in the gastropod shell plate and co-option of the dpp signaling pathway in the evolution of the operculum.
The operculum is a novel structure in gastropod molluscs. Because the operculum shows notable similarities to the shell plate, we… (More)
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Highly Cited
2012
Highly Cited
2012
Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.
Inappropriately low expression of the key iron regulator hepcidin (HAMP) causes iron overload in untransfused patients affected… (More)
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2001
2001
The Drosophila tumor suppressor gene lethal(2)giant larvae is required for the emission of the Decapentaplegic signal.
The Drosophila tumor suppressor gene lethal(2) giant larvae (lgl) encodes a cytoskeletal protein required for the change in shape… (More)
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2001
2001
A screen for modifiers of decapentaplegic mutant phenotypes identifies lilliputian, the only member of the Fragile-X/Burkitt's Lymphoma family of transcription factors in Drosophila melanogaster.
The decapentaplegic (dpp) gene directs numerous developmental events in Drosophila melanogaster. dpp encodes a member of the… (More)
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Highly Cited
1998
Highly Cited
1998
The Drosophila Medea gene is required downstream of dpp and encodes a functional homolog of human Smad4.
The Transforming Growth Factor-beta superfamily member decapentaplegic (dpp) acts as an extracellular morphogen to pattern the… (More)
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Highly Cited
1995
Highly Cited
1995
Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila.
Pathways for regulation of signaling by transforming growth factor-beta family members are poorly understood at present. The best… (More)
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Highly Cited
1995
Highly Cited
1995
schnurri is required for drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1
Cytokines of the TGF beta superfamily regulate many aspects of cellular function by activating receptor complexes consisting of… (More)
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