debromohymenialdisine

Known as: DBHA-SKF 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2016
01219952016

Papers overview

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2012
2012
Natural products have been the subject of interest for drug discovery and as tools for understanding the underlying cellular… (More)
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2010
2010
BACKGROUND AND PURPOSE Checkpoint kinase 2 (CHK2) is activated by DNA damage and can contribute to p53 stabilization, modulating… (More)
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2009
2009
Subsets of cells with stem-like properties have been previously isolated from human epithelial cancers and their resistance to… (More)
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Highly Cited
2008
Highly Cited
2008
Atypical teratoid/rhabdoid tumor (AT/RT) is an extremely malignant neoplasm in the central nervous system (CNS) which occurs in… (More)
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2006
2006
The protein kinase Chk2 (checkpoint kinase 2) is a major effector of the replication checkpoint. Chk2 activation is initiated by… (More)
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2004
2004
ACK1 is a multidomain non-receptor tyrosine kinase that is an effector of the Cdc42 GTPase. Members of the ACK family have a… (More)
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2004
2004
The marine sponge metabolite hymenialdisine is a potent inhibitor of a variety of kinases including MEK-1, GSK-3 beta, and CK1… (More)
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2003
2003
Activation of Cdc2/cyclin B kinase and entry into mitosis requires dephosphorylation of inhibitory sites on Cdc2 by Cdc25… (More)
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2001
2001
Cells can respond to DNA damage by activating checkpoints that delay cell cycle progression and allow time for DNA repair… (More)
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1995
1995
Analysis of the tropical marine sponge Axinella carteri afforded six unusual alkaloids, including the new brominated guanidine… (More)
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