deacylation
National Institutes of Health
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Class D beta-lactamases hydrolyze beta-lactam antibiotics by using an active site serine nucleophile to form a covalent acyl…
ABSTRACT Influenza virus hemagglutinin (HA) has three highly conserved acylation sites close to the carboxyl terminus of the HA2…
Kinetic interactions of beta-lactam antibiotics such as penicillin-G and cefotaxime with normal, penicillin-susceptible PBP2x…
Lysine 73 is a conserved active-site residue in the class A beta-lactamases, as well as other members of the serine penicillin…
Deacylation of purified lipopolysaccharides (LPS) markedly reduces its toxicity toward mammals. However, the biological…
The G238S substitution found in extended-spectrum natural mutants of TEM-1 beta-lactamase induces a new capacity to hydrolyze…
Hydrogenation of baccatin III over platinum converted it to its hexahydro derivative, and deacylation of this as its 7…
Inhibited chymotrypsin was reactivated through the photolysis of the covalently bound light-reversible cinnamates described in…
N-Hydroxyphenacetin was activated to a mutagen in the Salmonella-Ames test by rabbit liver acyltransferase, rat liver cytosol…