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daurisoline

Known as: (R-(R*,R*))-1,2,3,4-tetrahydro-1-((4-hydroxy-3-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)phenyl)methyl)-6-methoxy-2-methyl-7-iso quinolinol 
 
National Institutes of Health

Papers overview

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2019
2019
Acid-sensing ion channels (ASICs) are proton-gated sodium-selective channels that are expressed in the peripheral and central… Expand
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2017
2017
Autophagy is a cellular bulk degradation pathway implicated in various diseases. Inhibition of autophagy has been regarded as a… Expand
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2012
2012
Daurisoline (1) is a bis-benzylisoquinoline alkaloid isolated from the rhizomes of Menispermum dauricum. The antiarrhythmic… Expand
2010
2010
Our previous studies have shown that daurisoline (DS) exerted antiarrhythmic effects on various experimental arrhythmias. In this… Expand
2003
2003
AIM To study the combined pharmacokinetic-pharmacodynamic (PK-PD) model of daurisoline and dauricine, and compare their effects… Expand
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2002
2002
  • L. He, G. Liu
  • Acta pharmacologica Sinica
  • 2002
  • Corpus ID: 23589129
AIM To search for novel effective P-glycoprotein (P-gp) reversal agents in the blood-brain barrier (BBB). METHODS Using… Expand
2002
2002
  • L. He, G. Liu
  • Acta pharmacologica Sinica
  • 2002
  • Corpus ID: 23999345
AIM To gain further insights into the mechanism of the ATP-dependent interaction of P-glycoprotein (P-gp) with various multidrug… Expand
1998
1998
The neuroprotective effects of (-)-S.R-daurisoline on glutamate-induced neurotoxicity were studied in rat primary cortical… Expand
1994
1994
In looking for a structurally defined non-peptide P- channel blocker we have tested the alkaloid daurisoline which has been… Expand
1993
1993
Dauricoside (1), a new glycosidal alkaloid, was isolated from the rhizomes of Menispermum dauricum DC. along with dauricine (2… Expand