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darbufelone

National Institutes of Health

Papers overview

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2019
2019
In this work two series of isoindolines 1(a-g) and 2(a-g) were evaluated as possible inhibitors of lipoxygenase (LOX) by docking… 
2016
2016
Inflammation is emerging as a new hallmark of cancer. Arachidonic acid (AA) metabolism, the family of cyclooxygenases (COXs) and… 
2011
2011
Objective To evaluate the effect of darbufelone,a 5-lipoxygenase/cyclooxygenase-2(5-LOX/COX-2) dual inhibitor,on the growth of… 
Highly Cited
2009
Highly Cited
2009
A series of novel 4-Benzyl-1,3-thiazole derivatives was synthesized by applying analogue-based drug design approach and they were… 
2009
2009
PurposeInflammation plays a crucial role in the development of lung cancer. Accumulated studies have proved that non-steroidal… 
2009
2009
Aim To investigate the effects of dual COX-2/5-LOX inhibitor darbufelone on the inhibition of gastric adenocarcinoma in vitro… 
2007
2007
OBJECTIVE To synthesize Darbufelone,a new non-steroid anti-inflammatory drugs.METHODS 3,5-di-tert-butyl-4-hydroxy benzaldehyde… 
2001
2001
The antiinflammatory agent darbufelone, ((Z)-5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl] methylene]-2-imino-4-thiazolidinone…