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cytofectin

Known as: N,N-dimethylaminopropylamidosuccinylcholesterylformylhydrazide 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

CholesterolHydrazines
analogs & derivatives

Papers overview

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2011
2011
Cytofectin Amine Head Group Modification and Degree of Liposome Pegylation: Factors Influencing Gene Transfer
The effectiveness of liposome-mediated gene transfer methods hinges, in part, on the nature of the interaction between the DNA… 
2008
2008
Biophysical Properties of CDAN/DOPE‐Analogue Lipoplexes Account for Enhanced Gene Delivery
Typically, cationic liposomes are formulated from the combination of a synthetic cationic lipid (cytofectin) and a neutral… 
2006
2006
[Experimental study of antisense oligodeoxynucleotide targeting survivin gene for cisplatin resistant human lung adeno-carcinoma xenograft in nude mice].
OBJECTIVE To explore the feasibility of antisense oligodeoxynucleotide (ASODN) targeting survivin gene for cisplatin resistant… 
2005
2005
What Role Can Chemistry Play in Cationic Liposome-Based Gene Therapy Research Today?
2003
2003
Effect of cytofectins on the immune response of murine macrophages to mammalian DNA
DNA, depending on base sequence, can induce a wide range of immune responses. While bacterial DNA is stimulatory, mammalian DNA… 
Highly Cited
2002
Highly Cited
2002
Synergy between cationic lipid and co-lipid determines the macroscopic structure and transfection activity of lipoplexes.
The large number of cytofectin and co-lipid combinations currently used for lipoplex-mediated gene delivery reflects the fact… 
1997
1997
Tissue distribution of the cytofectin component of a plasmid-DNA/cationic lipid complex following intravenous administration in mice.
Allovectin-7 is a gene therapy agent that consists of plasmid DNA (pDNA) encoding the human HLA-B7 class I and beta2… 
1996
1996
Active cytofectin: polyfunctional cationic cytofectins for producing polynucleotide transfection complexes, formulations and methods
(57) Abstract: transfection of cells, formulations, counterions, and amine-containing compounds and cytofectins for reaction… 
1996
1996
Polyfumktionelle cationic cytofectins, formulations and methods of preparing active cytofectin: polynucleotide transfection-complex
Highly Cited
1996
Highly Cited
1996
Structural and functional analysis of cationic transfection lipids: the hydrophobic domain.
Cationic lipids (cytofectins) have gained widespread acceptance as pharmaceutical polynucleotide delivery agents for both… 
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