FAQ

cysteine-S-conjugate beta-lyase activity

Known as: L-cysteine-S-conjugate thiol-lyase (deaminating) activity, glutamine transaminase K/cysteine conjugate beta-lyase activity, cysteine-S-conjugate b-lyase activity 
Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate. [EC:4.4.1.13, MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-1992
01219821992

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1992
1992
High-performance liquid chromatography-fluorescence assay of pyruvic acid to determine cysteine conjugate beta-lyase activity: application to S-1,2-dichlorovinyl-L-cysteine and S-2-benzothiazolyl-L…
An HPLC-fluorescence assay has been developed for the determination of the activity of rat renal cytosolic cysteine conjugate… (More)
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1990
1990
Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity.
The central role of cysteine conjugate beta-lyase (beta-lyase) in the bioactivation of nephrotoxic halogenated hydrocarbons and… (More)
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1987
1987
Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine.
Renal cysteine conjugate beta-lyase (beta-lyase) catalyzes the bioactivation of nephrotoxic cysteine S-conjugates. beta-Lyase… (More)
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1987
1987
Evidence for involvement of non-biliary excretion into the intestines in the formation of methylsulphonyl-containing metabolites of 2-chloro-N-isopropylacetanilide (propachlor) by swine and rats.
1. Radiolabelled metabolites excreted in the urine of swine after an oral dose of 14C-propachlor were similar to those previously… (More)
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1985
1985
Isolation and characterization of a rat liver enzyme with both cysteine conjugate beta-lyase and kynureninase activity.
Cysteine conjugate beta-lyase is a name applied to enzymes which cleave the S-cysteine conjugates of some xenobiotics to pyruvate… (More)
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1985
1985
Cysteine conjugate beta-lyase activities in rat kidney cortex: subcellular localization and relationship to the hepatic enzyme.
Kidney cortex cysteine conjugate beta-lyase enzymes were characterized using S-(2-benzothiazolyl)-L-cysteine and S-(1,2… (More)
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1982
1982
Assay of cysteine conjugate beta-lyase activity with S-(2-benzothiazolyl)cysteine as the substrate.
 
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