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cyclodisone

Known as: 1,5,2,4-dioxadithiepane-2,2,4,4-tetraoxide 
A cyclic sulfonate ester with potential antineoplastic activity. As an alkylating agent, clyclodisone induces the formation of DNA interstrand… 
National Institutes of Health

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2 relations

Narrower (1)

NSC 348948

Broader (1)

Thiepins

Papers overview

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2004
2004
Inhibition of cellular esterases by the antitumour imidazotetrazines mitozolomide and temozolomide: demonstration by flow cytometry and conventional spectrofluorimetry
SummaryUsing flow cytometry and conventional spectrofluorimetry we have previously shown that chloroethylnitrosoureas (CNUs) can… 
1991
1991
Structure activity analysis of the formation of DNA damage induced in human tumor cells by the cyclodisone class of anti-tumor agent.
1,5,2,4-dioxadithiocane-2,2,4,4-tetraoxide (compound II) and 1,5,2,4-dioxadithionane-2,2,4,4-tetraoxide (compound III) are two… 
1989
1989
Characterization of DNA damage and cytotoxicity induced in two human colon carcinoma cell lines by cyclodisone.
Cyclodisone is an active alkylating antitumor agent that is being considered for Phase 1 clinical trials in humans and is… 
1988
1988
Comparison of the in vitro cytotoxicity of cyclodisone with a series of structurally related analogues.
: The in vitro cytotoxicity of a series of cyclic and linear sulfonate esters has been tested against the BE and HT-29 human… 
1988
1988
Comparison of the in vitro cytotoxicity of cyclodisone with a series of structurally related analogues.
The in vitro cytotoxicity of a series of cyclic and linear sulfonate esters has been tested against the BE and HT-29 human colon… 
1987
1987
Development of reversed-phase HPLC assays for cyclodisone and clomesone.
1986
1986
DNA reactivity and in vitro cytotoxicity of the novel antitumor agent 1,5,2,4-dioxadithiepane-2,2,4,4-tetraoxide (NSC-348948) in human embryo cells.
1,5,2,4-Dioxadithiepane-2,2,4,4-tetraoxide (cyclic-SoSo) is structurally a novel synthetic compound but may functionally act as… 
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