cyclic nucleotide-gated mechanosensitive ion channel activity

Known as: cyclic nucleotide regulated mechanosensitive ion channel, MscS, cyclic nucleotide gated mechanosensitive ion channel activity 
Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Concise Review: MSC-Derived Exosomes for Cell-Free Therapy.
Mesenchymal stem cell transplantation is undergoing extensive evaluation as a cellular therapy in human clinical trials. Because… (More)
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Review
2015
Review
2015
United in diversity: mechanosensitive ion channels in plants.
Mechanosensitive (MS) ion channels are a common mechanism for perceiving and responding to mechanical force. This class of… (More)
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Highly Cited
2010
Highly Cited
2010
IL-6-Dependent PGE2 Secretion by Mesenchymal Stem Cells Inhibits Local Inflammation in Experimental Arthritis
BACKGROUND Based on their capacity to suppress immune responses, multipotent mesenchymal stromal cells (MSC) are intensively… (More)
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Highly Cited
2007
Highly Cited
2007
Short-Term Exposure of Multipotent Stromal Cells to Low Oxygen Increases Their Expression of CX3CR1 and CXCR4 and Their Engraftment In Vivo
The ability of stem/progenitor cells to migrate and engraft into host tissues is key to their potential use in gene and cell… (More)
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Highly Cited
2006
Highly Cited
2006
MscS-like Proteins Control Plastid Size and Shape in Arabidopsis thaliana
BACKGROUND Mechanosensitive (MS) ion channels provide a mechanism for the perception of mechanical stimuli such as sound, touch… (More)
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Review
2003
Review
2003
Two families of mechanosensitive channel proteins.
Mechanosensitive (MS) channels that provide protection against hypoosmotic shock are found in the membranes of organisms from the… (More)
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Highly Cited
2002
Highly Cited
2002
Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel.
The mechanosensitive channel of small conductance (MscS) responds both to stretching of the cell membrane and to membrane… (More)
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Highly Cited
1999
Highly Cited
1999
Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity.
Mechanosensitive channels are ubiquitous amongst bacterial cells and have been proposed to have major roles in the adaptation to… (More)
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Highly Cited
1999
Highly Cited
1999
Energetic and Spatial Parameters for Gating of the Bacterial Large Conductance Mechanosensitive Channel, MscL
MscL is multimeric protein that forms a large conductance mechanosensitive channel in the inner membrane of Escherichia coli… (More)
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Highly Cited
1994
Highly Cited
1994
A large-conductance mechanosensitive channel in E. coli encoded by mscL alone
ALL cellular organisms respond to vibration, touch, gravity or changes in osmolarity, although the molecules on which such… (More)
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