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cotransin

 
National Institutes of Health

Papers overview

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2016
2016
Apratoxin A is a cytotoxic natural product that prevents the biogenesis of secretory and membrane proteins. Biochemically… Expand
Review
2015
Review
2015
Protein translocation into the endoplasmic reticulum (ER) constitutes the first step of protein secretion. ER protein import is… Expand
2015
2015
ABSTRACT A new cyclic decadepsipeptide was isolated from Chaetosphaeria tulasneorum with potent bioactivity on mammalian and… Expand
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2015
2015
The cyclodepsipeptide cotransin was described to inhibit the biosynthesis of a small subset of proteins by a signal sequence… Expand
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Highly Cited
2014
Highly Cited
2014
Membrane protein biogenesis requires the coordinated movement of hydrophobic transmembrane domains (TMD) from the cytosolic… Expand
2013
2013
Although clusterin (CLU) was originally identified as a secreted glycoprotein that plays cytoprotective role, several… Expand
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2011
2011
The specific inhibition of the biosynthesis of target proteins is a relatively novel strategy in pharmacology and is based mainly… Expand
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2011
2011
Cotransins are cyclic heptadepsipeptides that bind the Sec61 translocon to inhibit cotranslational translocation of a subset of… Expand
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2008
2008
The first solid-phase synthesis of cotransin--a cyclic depsipeptide having high pharmacological potential--was achieved, by a… Expand
Highly Cited
2005
Highly Cited
2005
The segregation of secretory and membrane proteins to the mammalian endoplasmic reticulum is mediated by remarkably diverse… Expand
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