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cotransin

 
National Institutes of Health

Papers overview

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2016
2016
Apratoxin A is a cytotoxic natural product that prevents the biogenesis of secretory and membrane proteins. Biochemically… Expand
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2015
2015
A new cyclic decadepsipeptide was isolated from Chaetosphaeria tulasneorum with potent bioactivity on mammalian and yeast cells… Expand
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2015
2015
The cyclodepsipeptide cotransin was described to inhibit the biosynthesis of a small subset of proteins by a signal sequence… Expand
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Review
2015
Review
2015
Protein translocation into the endoplasmic reticulum (ER) constitutes the first step of protein secretion. ER protein import is… Expand
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2014
2014
Membrane protein biogenesis requires the coordinated movement of hydrophobic transmembrane domains (TMD) from the cytosolic… Expand
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2013
2013
Although clusterin (CLU) was originally identified as a secreted glycoprotein that plays cytoprotective role, several… Expand
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2011
2011
The specific inhibition of the biosynthesis of target proteins is a relatively novel strategy in pharmacology and is based mainly… Expand
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2011
2011
Cotransins are cyclic heptadepsipeptides that bind the Sec61 translocon to inhibit cotranslational translocation of a subset of… Expand
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2008
2008
The first solid-phase synthesis of cotransin--a cyclic depsipeptide having high pharmacological potential--was achieved, by a… Expand
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Highly Cited
2005
Highly Cited
2005
The segregation of secretory and membrane proteins to the mammalian endoplasmic reticulum is mediated by remarkably diverse… Expand
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