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combretastatin A-1

Known as: Combretastatin A1 
National Institutes of Health

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1 relation

Broader (1)

Stilbenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Computational Design and Synthesis of Novel Fluoro-Analogs of Combretastatins A-4 and A-1.
Review
2015
Review
2015
Recent advancement in discovery and development of natural product combretastatin-inspired anticancer agents.
The natural stilbenoids combretastatin A-4 (CA4) and combretastatin A-1 (CA1) are potent antitubulin agents demonstrating… 
2012
2012
A validated HPLC method with fluorescence detection for the glucuronides of Combretastatin A1 in human plasma, and studies on their cis-trans isomerisation.
2012
2012
Quantitative determination of the anticancer prodrug combretastatin A1 phosphate (OXi4503, CA1P), the active CA1 and its glucuronide metabolites in human urine and of CA1 in plasma by HPLC with mass…
2011
2011
Regioselective synthesis of water-soluble monophosphate derivatives of combretastatin A-1.
The natural products combretastatin A-4 (CA4) and combretastatin A-1 (CA1) are potent cancer vascular disrupting agents and… 
2010
2010
A multicenter, open-label phase Ib/II study to assess the safety and clinical activity of intravenous combretastatin A1 diphosphate (OXi4503) as monotherapy in subjects with primary or secondary…
TPS164 Background: Combretastatin A1 diphosphate (CA1P, OXi4503) is a novel vascular disrupting agent (VDA) that is a reversible… 
1997
1997
Effects of novel and conventional anti-cancer agents on human endothelial permeability: influence of tumour secreted factors.
A number of anti-cancer agents have been implicated in vascular toxicity. The effects have been attributed to direct drug… 
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