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columbin

Known as: 1,4-Etheno-3H,7H-benzo(1,2-c:3,4-c')dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, (1R-(1alpha,4beta,4aalpha,6abeta,9beta,10abeta,10balpha))- 
National Institutes of Health

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2 relations

Broader (2)

DiterpenesLactones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Cytochrome P450 Enzyme-Mediated Bioactivation as an Underlying Mechanism of Columbin-Induced Hepatotoxicity.
Columbin, a furanoid compound, is the major bioactive ingredient of Tinospora sagittata (Oliv.) Gagnep, a traditional Chinese… 
2017
2017
Semisynthesis and Kappa-Opioid Receptor Activity of Derivatives of Columbin, a Furanolactone Diterpene.
Columbin (1) is a furanolactone diterpene isolated from the roots of Jateorhiza and Tinospora species. These species generally… 
2016
2016
Protective Effects of Tinospora cordifolia on Hepatic and Gastrointestinal Toxicity Induced by Chronic and Moderate Alcoholism.
AIMS Heavy alcohol intake depletes the plasma vitamins due to hepatotoxicity and decreased intestinal absorption. However… 
2007
2007
Simultaneous determination of eight components in Radix Tinosporae by high-performance liquid chromatography coupled with diode array detector and electrospray tandem mass spectrometry.
2007
2007
Quantitative LC/MS/MS method and pharmacokinetic studies of columbin, an anti-inflammation furanoditerpen isolated from Radix Tinosporae.
Columbin is an important component isolated from Radix Tinosporae. It has been demonstrated to possess many pharmacological… 
Highly Cited
2006
Highly Cited
2006
Anti-inflammatory activities of the methanol extracts and an isolated furanoditerpene constituent of Sphenocentrum jollyanum Pierre (Menispermaceae).
2006
2006
Clerodanes and other constituents of Cleidion spiciflorum.
2005
2005
Columbin inhibits cholesterol uptake in bloodstream forms of Trypanosoma brucei-A possible trypanocidal mechanism
The diterpenoid furanolactone (columbin) from Aristolochia albida inhibited growth of culture forms of Trypanosoma brucei. In… 
1995
1995
Columbin isolated from calumbae radix affects the sleeping time of anesthetized mice.
In a screening series of bioactive components in edible and medicinal plants, we found that Calumbae Radix (Colombo root, 1… 
1989
1989
Structure of columbin, a diterpenoid furanolactone from Tinospora cordifolia Miers.
(1S,4R,5R,8S,10R,12S)-4-Hydroxy-15,16-epoxycleroda-2,12(16),14- trieno-17,12: 18,1-biscarbolactone, C20H22O6, Mr = 358.2, m.p… 
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