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cobaltiprotoporphyrin

Known as: cobalt protoporphyrin, cobalt protoporphyrin IX 
National Institutes of Health

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Protoporphyrins

Papers overview

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2013
2013
Inducer of heme oxygenase‐1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during lipopolysaccharide treatment in rat liver
Aim:  Mitochondrial damage and subsequent oxidative stresses play important roles in the pathogenesis of sepsis‐induced organ… 
Highly Cited
2012
Highly Cited
2012
Induction of hemeoxygenase-1 reduces glomerular injury and apoptosis in diabetic spontaneously hypertensive rats.
Induction of hemeoxygenase-1 (HO-1) lowers blood pressure and reduces organ damage in hypertensive animal models; however, a… 
Highly Cited
2010
Highly Cited
2010
Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction.
OBJECTIVE To assess the effects of cilostazol in inhibiting proliferation and enhancing apoptosis in synovial cells from patients… 
1992
1992
Effects of hemin and porphyrin compounds on intersubunit disulfide formation of heme-regulated eIF-2 alpha kinase and the regulation of protein synthesis in reticulocyte lysates.
To study the mechanism by which heme regulates the heme-regulated eIF-2 alpha kinase (HRI), the effects of various protoporphyrin… 
1981
1981
Cobalt-substituted cytochrome P-450cam.
Reconstitution of the apo-cytochrome with cobalt protoporphyrin provides a faithful P-450cam analogue as characterized by optical… 
Highly Cited
1979
Highly Cited
1979
Purification and properties of heme oxygenase from rat liver microsomes.
Heme oxygenase was purified to apparent homogeneity from liver microsomes of rats which had been treated with either cobaltous… 
Highly Cited
1977
Highly Cited
1977
Enzymatic oxidation of cobalt protoporphyrin IX: observations on the mechanism of heme oxygenase action.
Studies on the enzymatic mechanism of microsomal heme oxygenase were made utilizing various porphyrins and metalloporphyrins of… 
Highly Cited
1973
Highly Cited
1973
Thermodynamics of ligand and oxygen binding to cobalt protoporphyrin IX dimethyl ester in toluene solution.
1973
1973
Stereochemical trigger for initiating cooperative interaction of the subunits during the oxygenation of cobaltohemoglobin.
Relative to the standard provided by an unconstrained five-coordinate imidazoleiron(II) porphyrin, the axial separation (N… 
Highly Cited
1969
Highly Cited
1969
The structural organization of haem synthesis in rat liver mitochondria.
1. Anaerobic conditions are normally necessary for incorporation of iron into haems and only ferrous iron is used. After addition… 
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