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cloxyquin
Known as:
5-chloroquinolin-8-ol
A monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa. Cloxyquin is reported to have activity against…
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Antibiotics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Insight into the Molecular Interaction of Cloxyquin (5-chloro-8-hydroxyquinoline) with Bovine Serum Albumin: Biophysical Analysis and Computational Simulation
Kamonrat Phopin
,
Waralee Ruankham
,
Supaluk Prachayasittikul
,
V. Prachayasittikul
,
Tanawut Tantimongcolwat
International journal of molecular sciences
2019
Corpus ID: 210042889
Cloxyquin is a potential therapeutic compound possessing various bioactivities, especially antibacterial, antifungal…
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2017
2017
Selective and state‐dependent activation of TRESK (K2P18.1) background potassium channel by cloxyquin
M. Lengyel
,
Alice Dobolyi
,
G. Czirják
,
P. Enyedi
British journal of pharmacology
2017
Corpus ID: 20794062
Cloxyquin (5‐cloroquinolin‐8‐ol) has been described as an activator of TRESK (K2P18.1, TWIK‐related spinal cord K+ channel…
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Highly Cited
2016
Highly Cited
2016
Derivatives (halogen, nitro and amino) of 8-hydroxyquinoline with highly potent antimicrobial and antioxidant activities
R. Cherdtrakulkiat
,
S. Boonpangrak
,
Nujarin Sinthupoom
,
Supaluk Prachayasittikul
,
S. Ruchirawat
,
V. Prachayasittikul
Biochemistry and biophysics reports
2016
Corpus ID: 34480568
2016
2016
The cardioprotective compound cloxyquin uncouples mitochondria and induces autophagy.
Jimmy Zhang
,
S. Nadtochiy
,
William R. Urciuoli
,
P. Brookes
American journal of physiology. Heart and…
2016
Corpus ID: 32104810
Mitochondrial quality control mechanisms have been implicated in protection against cardiac ischemia-reperfusion (IR) injury…
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2016
2016
Development of a novel sulfonate ester-based prodrug strategy.
Kengo Hanaya
,
Shohei Yoshioka
,
Shinya Ariyasu
,
S. Aoki
,
Mitsuru Shoji
,
T. Sugai
Bioorganic & medicinal chemistry letters
2016
Corpus ID: 30593199
2013
2013
Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK.
P. Wright
,
Gregory Weir
,
+4 authors
J. Jerman
Biochemical and biophysical research…
2013
Corpus ID: 22305144
TRESK is a two-pore domain potassium channel. Loss of function mutations have been linked to typical migraine with aura and due…
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Review
2012
Review
2012
Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy
Andrew Walters
,
G. Porter
,
P. Brookes
Circulation research
2012
Corpus ID: 1861158
Ischemic heart disease is a significant cause of morbidity and mortality in Western society. Although interventions, such as…
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2012
2012
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation
Sifei Xing
,
S. Bhat
,
+5 authors
R. Siliciano
The Journal of antimicrobial chemotherapy
2012
Corpus ID: 12873908
Background The latent reservoir of HIV-1 in resting memory CD4+ T cells is a major barrier to curing HIV-1 infection. Eradication…
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2012
2012
RP-HPLC method for quantitative estimation of Halquinol in pharmaceutical dosage forms
N. Kandepu
,
Sharadamma C. Kodaganur
,
A. Mantri
,
S. Saha
,
Radhakrishna M. Pallipadi
2012
Corpus ID: 49365457
Halquinol is a mixture obtained by chlorinating 8-Hydroxy quinoline. It contains 5,7-dichloroquinolin-8-ol (57 to 74%), 5…
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Highly Cited
2006
Highly Cited
2006
In Vitro Activities of Cloxyquin (5-Chloroquinolin-8-ol) against Mycobacterium tuberculosis
P. Hongmanee
,
K. Rukseree
,
B. Buabut
,
Boontiwa Somsri
,
P. Palittapongarnpim
Antimicrobial Agents and Chemotherapy
2006
Corpus ID: 22545222
ABSTRACT The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of…
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