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cloxyquin

Known as: 5-chloroquinolin-8-ol 
A monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa. Cloxyquin is reported to have activity against… Expand
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Antibiotics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Selective and state‐dependent activation of TRESK (K2P18.1) background potassium channel by cloxyquin
Cloxyquin (5‐cloroquinolin‐8‐ol) has been described as an activator of TRESK (K2P18.1, TWIK‐related spinal cord K+ channel… Expand
2016
2016
Development of a novel sulfonate ester-based prodrug strategy.
A self-immolative γ-aminopropylsulfonate linker was investigated for use in the development of prodrugs that are reactive to… Expand
2016
2016
The cardioprotective compound cloxyquin uncouples mitochondria and induces autophagy.
Mitochondrial quality control mechanisms have been implicated in protection against cardiac ischemia-reperfusion (IR) injury… Expand
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2016
2016
Derivatives (halogen, nitro and amino) of 8-hydroxyquinoline with highly potent antimicrobial and antioxidant activities
8-Hydroxyquinoline (8HQ) compounds have been reported to possess diverse bioactivities. In recent years, drug repositioning has… Expand
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2013
2013
Cloxyquin (5-Chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK.
TRESK is a two-pore domain potassium channel. Loss of function mutations have been linked to typical migraine with aura and due… Expand
2013
2013
Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK.
TRESK is a two-pore domain potassium channel. Loss of function mutations have been linked to typical migraine with aura and due… Expand
2012
2012
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation
Background The latent reservoir of HIV-1 in resting memory CD4+ T cells is a major barrier to curing HIV-1 infection. Eradication… Expand
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2012
2012
Novel anti-Cryptosporidium activity of known drugs identified by high-throughput screening against parasite fatty acyl-CoA binding protein (ACBP).
BACKGROUND Cryptosporidium parvum causes an opportunistic infection in AIDS patients, and no effective treatments are yet… Expand
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2006
2006
In Vitro Activities of Cloxyquin (5-Chloroquinolin-8-ol) against Mycobacterium tuberculosis
ABSTRACT The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of… Expand
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1995
1995
Contact dermatitis from cloxyquin
case presented with classical features of plant dermatitis. Interestingly, all presented during the autumn (fall) when the tree… Expand
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