Skip to search formSkip to main contentSkip to account menu

cloxyquin

Known as: 5-chloroquinolin-8-ol 
A monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa. Cloxyquin is reported to have activity against… 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Antibiotics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Insight into the Molecular Interaction of Cloxyquin (5-chloro-8-hydroxyquinoline) with Bovine Serum Albumin: Biophysical Analysis and Computational Simulation
Cloxyquin is a potential therapeutic compound possessing various bioactivities, especially antibacterial, antifungal… 
2017
2017
Selective and state‐dependent activation of TRESK (K2P18.1) background potassium channel by cloxyquin
Cloxyquin (5‐cloroquinolin‐8‐ol) has been described as an activator of TRESK (K2P18.1, TWIK‐related spinal cord K+ channel… 
Highly Cited
2016
Highly Cited
2016
Derivatives (halogen, nitro and amino) of 8-hydroxyquinoline with highly potent antimicrobial and antioxidant activities
2016
2016
The cardioprotective compound cloxyquin uncouples mitochondria and induces autophagy.
Mitochondrial quality control mechanisms have been implicated in protection against cardiac ischemia-reperfusion (IR) injury… 
2016
2016
Development of a novel sulfonate ester-based prodrug strategy.
2013
2013
Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK.
TRESK is a two-pore domain potassium channel. Loss of function mutations have been linked to typical migraine with aura and due… 
Review
2012
Review
2012
Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy
Ischemic heart disease is a significant cause of morbidity and mortality in Western society. Although interventions, such as… 
2012
2012
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation
Background The latent reservoir of HIV-1 in resting memory CD4+ T cells is a major barrier to curing HIV-1 infection. Eradication… 
2012
2012
RP-HPLC method for quantitative estimation of Halquinol in pharmaceutical dosage forms
Halquinol is a mixture obtained by chlorinating 8-Hydroxy quinoline. It contains 5,7-dichloroquinolin-8-ol (57 to 74%), 5… 
Highly Cited
2006
Highly Cited
2006
In Vitro Activities of Cloxyquin (5-Chloroquinolin-8-ol) against Mycobacterium tuberculosis
ABSTRACT The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License