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cleavase

National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Gene targeting by homologous recombination (HR) can be induced by double-strand breaks (DSBs), however these breaks can be toxic… Expand
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2008
2008
  • A. Ogawa, M. Maeda
  • Bioorganic & medicinal chemistry letters
  • 2008
  • Corpus ID: 19628947
We developed a method for simply and rapidly detecting cofactors of aptazymes with high sensitivity using unique noncrosslinking… Expand
Review
2005
Review
2005
  • M. Olivier
  • Mutation research
  • 2005
  • Corpus ID: 37408841
The Invader assay uses a structure-specific flap endonuclease (FEN) to cleave a three-dimensional complex formed by hybridization… Expand
2004
2004
The CFLP methodology was applied for Cleavase I site detection within ptDNA intergenic regions (atpB-rbcL and rps14-psaB) at both… Expand
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1999
1999
The removal of impurities and contaminants from PCR‐amplified fragments is important for mutation detection methods which… Expand
1999
1999
Cleavase® fragment length polymorphism (CFLP) is a newly developed method used for the detection of gene mutation. This study… Expand
1998
1998
  • Wei, Killeen
  • Molecular diagnosis : a journal devoted to the…
  • 1998
  • Corpus ID: 8263251
Background: Congenital adrenal hyperplasia (CAH) owing to steroid 21-hydroxylase deficiency results from mutations in CYP21. The… Expand
1998
1998
Background: Genetic screening requires methods for mutation detection that are sensitive, precise, and robust. In population… Expand
Highly Cited
1997
Highly Cited
1997
We describe the application of a new DNA-scanning method, which has been termed Cleavase Fragment Length Polymorphism (CFLP… Expand
Highly Cited
1996
Highly Cited
1996
We describe here a new approach for analyzing nucleic acid sequences using a structure-specific endonuclease, Cleavase I. We have… Expand