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Cancer cells use alternate energetic pathways; however, cancer stem cell (CSC) metabolic energetic pathways are unknown. The… Expand AbstractPurpose
Focal adhesion kinase is an important survival signal in cancer. Recently, we demonstrated that the… Expand Acetaldehyde dehydrogenase (E.C. 220.127.116.11) plays a key role in the acetaldehyde detoxification. The recombinant Escherichia coli… Expand Acetaldehyde is a known mutagen and carcinogen. Active aldehyde dehydrogenase (ALDH) represents an important mechanism for… Expand Over the past 15 years, mechanistic and structural aspects were studied extensively for hydrolytic ALDHs. One the most striking… Expand The single nucleotide polymorphism (SNP) of aldehyde dehydrogenase-2 (ALDH2) codon 487, GAA (Glu) or AAA (Lys), was examined… Expand Alcohol dehydrogenases (ADHs) of the MDR type (medium-chain dehydrogenases/reductases) have diverged into two evolutionary groups… Expand Mammalian class I aldehyde dehydrogenase (ALDH1) has been implicated as a retinal dehydrogenase in the biosynthesis of retinoic… Expand The effects of certain experimental variables on rodents brain and liver alcohol--(ADH) and aldehyde-dehydrogenase (LALDH) were… Expand The velocity of acetaldehyde metabolism in rat liver may be governed either by the rate of regeneration of NAD from NADH through… Expand