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cis-Urocanic Acid

Known as: cis-UCA 
A derivative of the amino acid histidine, formed in the mammalian skin from trans-urocanic acid upon ultraviolet radiation, and protodynamic agent… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Urocanic acid (UCA) is present at millimolar concentrations in mammalian epidermis and undergoes photoisomerization from the… Expand
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Highly Cited
2001
Highly Cited
2001
UV radiation induces skin cancer primarily by its DNA-damaging properties, but also by its capacity to suppress the immune system… Expand
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Highly Cited
1997
Highly Cited
1997
Studies in experimental models have implicated histamine and prostanoids in ultra‐violet B (UVB)‐ and cis‐urocanic acid (UCA… Expand
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Highly Cited
1995
Highly Cited
1995
Abstract— There is considerable evidence that suppression of the immune system by UVB (280–320 nm UV) irradiation is initiated by… Expand
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Highly Cited
1994
Highly Cited
1994
Spectroscopic properties of chymotrypsin and model compounds indicate that a low-barrier hydrogen bond participates in the… Expand
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Highly Cited
1994
Highly Cited
1994
Irradiation with ultraviolet B light (UVB) is known to suppress contact and delayed hypersensitivity response to a variety of… Expand
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Highly Cited
1993
Highly Cited
1993
Cis-urocanic acid (cis-UCA), which is formed from the naturally occurring trans-isomer on ultraviolet (UV) irradiation, has been… Expand
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Highly Cited
1992
Highly Cited
1992
Ultraviolet B (UVB) light impairs the induction of contact hypersensitivity to epicutaneously applied haptens in certain strains… Expand
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Review
1989
Review
1989
Urocanic acid, a molecule found at high concentration in the stratum corneum, acts as a photoreceptor for UV‐light, isomerizing… Expand
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Highly Cited
1988
Highly Cited
1988
Urocanic acid (UCA, deaminated histidine) is a major ultraviolet-absorbing component of the stratum corneum. On UV irradiation… Expand
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