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ciproxifan

Known as: cyclopropyl-(4-(3-1H-imidazol-4-yl)propyloxyphenyl)ketone 
National Institutes of Health

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2 relations

Broader (2)

Histamine H3 AntagonistsImidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The histaminergic H1, H2, and H3 receptors of the lateral septum differentially mediate the anxiolytic-like effects of histamine on rats' defensive behaviors in the elevated plus maze and novelty…
2012
2012
Awakening properties of newly discovered highly selective H3 receptor antagonists in rats
2012
2012
In vivo receptor occupancy assay of histamine H₃ receptor antagonist in rats using non-radiolabeled tracer.
2009
2009
11C-GSK189254: A Selective Radioligand for In Vivo Central Nervous System Imaging of Histamine H3 Receptors by PET
The histamine H3 receptor is a G-protein–coupled presynaptic auto- and heteroreceptor whose activation leads to a decrease in the… 
2005
2005
Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug–drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs
2002
2002
Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model
2002
2002
Ligands for histamine H3 receptors modulate cell proliferation and migration in rat oxyntic mucosa
(R)‐α‐methylhistamine, a selective agonist of histamine H3 receptors, promotes mucus secretion and increases the number and… 
2000
2000
Novel histamine H(3)-receptor antagonists with carbonyl-substituted 4-(3-(phenoxy)propyl)-1H-imidazole structures like ciproxifan and related compounds.
Novel histamine H(3)-receptor antagonists possessing a 4-(3-(phenoxy)propyl)-1H-imidazole structure generally substituted in the… 
2000
2000
Ciproxifan and cimetidine modulate c-fos expression in septal neurons, and acetylcholine release from hippocampus of freely moving rats
The protoncogene c-fos is an immediate-early gene linked to genomic events in the cellular response to environmental signals [1… 
1998
1998
Ciproxifan and chemically related compounds are highly potent and selective histamine H3-receptor antagonists
We determined the affinities of five newly synthesized histamine H3-receptor antagonists in an H3-receptor binding assay and… 
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