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chronic ulcer of lower extremity

Known as: chronic leg ulcer, chronic leg ulcers 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Evidence on the use of platelet-rich plasma for diabetic ulcer: A systematic review
The aim of topical wound treatment is to favor efficient, rapid, and safe healing. The platelet-rich plasma (PRP) has been used… 
Highly Cited
2010
Highly Cited
2010
A Clinical Investigation into the Relationship between Increased Periwound Skin Temperature and Local Wound Infection in Patients with Chronic Leg Ulcers
PURPOSE:To enhance the clinician's knowledge about the relationship between increased periwound skin temperature and local wound… 
Highly Cited
2008
Highly Cited
2008
Autologous platelet‐rich fibrin matrix as cell therapy in the healing of chronic lower‐extremity ulcers
A novel autologous platelet‐rich fibrin matrix membrane (PRFM) was assessed for the ability to facilitate healing in patients… 
Review
2008
Review
2008
HGF as a renotrophic and anti-fibrotic regulator in chronic renal disease.
Hepatocyte growth factor (HGF) and Met/HGF receptor play roles in dynamic growth and morphogenesis during development and… 
Highly Cited
2003
Highly Cited
2003
Effect of electrical stimulation on chronic leg ulcer size and appearance.
BACKGROUND AND PURPOSE Electrical current has been recommended for use on chronic pressure ulcers; however, the ability of this… 
Review
2001
Review
2001
Use of molecular techniques to study microbial diversity in the skin: Chronic wounds reevaluated
The skin is colonized by an array of microorganisms which form its natural microflora. Disruption to the normal barrier function… 
Review
1999
Review
1999
Patients with chronic leg ulcers show diminished levels of vitamins A and E, carotenes, and zinc.
BACKGROUND Nutrition plays an important role in the wound healing process, particularly in the elderly. OBJECTIVE Comparison of… 
Review
1998
Review
1998
Does oral zinc aid the healing of chronic leg ulcers? A systematic literature review.
OBJECTIVE To determine whether oral zinc sulfate is an effective treatment for promoting healing of venous or arterial leg ulcers… 
Highly Cited
1991
Highly Cited
1991
Epidemiology of chronic venous ulcers
A metropolitan population of 238000 in Perth, Western Australia, was screened for chronic ulceration of the leg. Patients with a… 
Highly Cited
1990
Highly Cited
1990
EVIDENCE THAT HUMAN ORAL EPITHELIUM RECONSTITUTED IN VITRO AND TRANSPLANTED ONTO PATIENTS WITH DEFECTS IN THE ORAL MUCOSA RETAINS PROPERTIES OF THE ORIGINAL DONOR SITE1
Normal human skin—derived keratinocytes cultured in vitro reconstitute a stratified epidermis suitable for grafting onto burn… 
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