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ceramide 1-phosphate

 
National Institutes of Health

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Broader (1)

Ceramides

Papers overview

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2013
2013
Ceramide 1-phosphate induces macrophage chemoattractant protein-1 release: involvement in ceramide 1-phosphate-stimulated cell migration.
The bioactive sphingolipid ceramide 1-phosphate (C1P) is implicated in inflammatory responses and was recently shown to promote… Expand
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2013
2013
Ceramide 1-phosphate stimulates glucose uptake in macrophages.
It is well established that ceramide 1-phosphate (C1P) is mitogenic and antiapoptotic, and that it is implicated in the… Expand
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2011
2011
Activation of mTOR and RhoA is a major mechanism by which Ceramide 1-phosphate stimulates macrophage proliferation.
This study tested the hypothesis that Ceramide 1-phosphate (C1P) stimulates macrophage proliferation through activation of the… Expand
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Highly Cited
2009
Highly Cited
2009
Ceramide 1-phosphate (C1P) promotes cell migration Involvement of a specific C1P receptor.
Ceramide 1-phosphate (C1P) is a bioactive sphingolipid that is implicated in the regulation of cell homeostasis and the control… Expand
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Highly Cited
2008
Highly Cited
2008
Ceramide 1-phosphate stimulates macrophage proliferation through activation of the PI3-kinase/PKB, JNK and ERK1/2 pathways.
Ceramide 1-phosphate (C1P) was first shown to be mitogenic for fibroblasts, but the mechanisms whereby it stimulated cell… Expand
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Review
2005
Review
2005
Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling.
The phosphorylated sphingolipid metabolites sphingosine 1-phosphate (S1P) and ceramide 1-phosphate (C1P) have emerged as potent… Expand
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Highly Cited
2005
Highly Cited
2005
Ceramide 1-phosphate acts as a positive allosteric activator of group IVA cytosolic phospholipase A2 alpha and enhances the interaction of the enzyme with phosphatidylcholine.
Previous findings from our laboratory have demonstrated that cPLA(2)alpha is directly activated by the emerging bioactive… Expand
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Review
2004
Review
2004
Lipid phosphate phosphatases and related proteins: signaling functions in development, cell division, and cancer.
Lipid phosphates initiate key signaling cascades in cell activation. Lysophosphatidate (LPA) and sphingosine 1-phosphate (S1P… Expand
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Highly Cited
2004
Highly Cited
2004
Ceramide kinase is a mediator of calcium-dependent degranulation in mast cells.
Ceramide kinase (CERK) catalyzes the conversion of ceramide to ceramide 1-phosphate (C1P) and is known to be activated by calcium… Expand
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Highly Cited
1997
Highly Cited
1997
Stimulation of DNA synthesis by natural ceramide 1-phosphate.
We found that natural (long-chain) ceramide 1-phosphate can be dispersed into aqueous solution when dissolved in an appropriate… Expand
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