ceramide 1-phosphate

The bioactive sphingolipid ceramide 1-phosphate (C1P) is implicated in inflammatory responses and was recently shown to promote… (More)

Recent studies have established specific cellular functions for different bioactive sphingolipids in skeletal muscle cells… (More)

Ceramide 1-phosphate (C1P) was first shown to be mitogenic for fibroblasts, but the mechanisms whereby it stimulated cell… (More)

The agonist-stimulated metabolism of membrane lipids produces potent second messengers that regulate phagocytosis. We studied… (More)

Recently, we demonstrated that ceramide kinase, and its product, ceramide 1-phosphate (Cer-1-P), were mediators of arachidonic… (More)

Lipid phosphate phosphohydrolase (LPP)-1 cDNA was cloned from a rat liver cDNA library. It codes for a 32-kDa protein that shares… (More)

We found that natural (long-chain) ceramide 1-phosphate can be dispersed into aqueous solution when dissolved in an appropriate… (More)

A Mg2+-independent phosphatidate phosphohydrolase was purified from rat liver plasma membranes in two distinct forms, an anionic… (More)

Recent studies have implicated sphingolipids in a variety of intracellular signaling systems. The finding that a calcium… (More)

Prior studies demonstrated that conversion of sphingomyelin to ceramide via sphingomyelinase action resulted in the generation of… (More)