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cephalosporin C

Known as: 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((5-amino-5-carboxy-1-oxopentyl)amino)-8-oxo-, (6R-(6 alpha,7 beta(R*)))- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cephalosporins

Narrower (1)

cephalosporin C, monozinc salt

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Strategic manipulation of an industrial biocatalyst – evolution of a cephalosporin C acylase
Semi‐synthetic cephalosporins are synthesized from the 7‐amino cephalosporanic acid (7‐ACA) nucleus produced from the antibiotic… 
2010
2010
Improvement of Cephalosporin C Production by Recombinant DNA Integration in Acremonium chrysogenum
Cephalosporins are widely used as anti-infectious β-lactam antibiotics in clinic. For the purpose of increasing the yield of… 
2010
2010
A single Phe54Tyr substitution improves the catalytic activity and thermostability of Trigonopsis variabilis D-amino acid oxidase.
2009
2009
Optimization of medium constituents for Cephalosporin C production using response surface methodology and artificial neural networks
Artificial neural networks (ANN) and response surface methodology (RSM) were used to build a model to describe the effects of… 
2006
2006
Process strategies for cephalosporin C fermentation
Cephalosporin C (CPC), a �-lactam antibiotic, is starting molecule for industrial production of semi synthetic cephalosporins… 
Highly Cited
1999
Highly Cited
1999
In vivo post-translational processing and subunit reconstitution of cephalosporin acylase from Pseudomonas sp. 130.
Cephalosporin acylases are a group of enzymes that hydrolyze cephalosporin C (CPC) and/or glutaryl 7-amino cephalosporanic acid… 
1996
1996
Oxidative modification of a cephalosporin C acylase from Pseudomonas strain N176 and site-directed mutagenesis of the gene
A cephalosporanic acid acylase from Pseudomonas strain N176 catalyzes hydrolysis of both glutarylcephalosporanic acid and… 
Highly Cited
1995
Highly Cited
1995
Two‐step immobilized enzyme conversion of cephalosporin C to 7‐aminocephalosporanic acid
The first large‐scale production of 7‐aminocephalosporanic acid (7ACA) from cephalosporin C (CPC) using a wholly enzymatic… 
1992
1992
Cloning and disruption of the cefG gene encoding acetyl coenzyme A: deacetylcephalosporin C o-acetyltransferase from Acremonium chrysogenum.
1991
1991
2-Nitro-5-(6-bromohexanoylamino)benzoic acid test paper method for detecting microorganisms capable of producing cephalosporin acylases.
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