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cellular targeting

Known as: Targeted, Targeting 
The process of directing an agent to a specific anatomic location.
National Institutes of Health

Related topics

Related topics

4 relations
Intracellular TransportSorting - Cell Movementcell motilityprotein transport

Papers overview

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Highly Cited
2007
Highly Cited
2007
Pioglitazone Inhibits In-Stent Restenosis in Atherosclerotic Rabbits by Targeting Transforming Growth Factor-&bgr; and MCP-1
Objective—Although emerging data from preclinical and clinical studies suggests a reduction of in-stent restenosis with… 
Highly Cited
2006
Highly Cited
2006
Phase I clinical evaluation of weekly administration of the novel vascular-targeting agent, ZD6126, in patients with solid tumors.
PURPOSE ZD6126 is a novel vascular-targeting agent that induces selective effects on the morphology of endothelial cells by… 
Highly Cited
2005
Highly Cited
2005
Targeting tumor angiogenesis: comparison of peptide and polymer-peptide conjugates.
UNLABELLED Endothelial cells in tumor angiogenesis are highly accessible, genetically stable and present unique molecular markers… 
Highly Cited
2004
Highly Cited
2004
Prospects for total synthesis: a vision for a totally synthetic vaccine targeting epithelial tumors.
Vaccines derived from totally synthetic carbohydrate antigens have been shown to elicit an immune response in both preclinical… 
Highly Cited
2003
Highly Cited
2003
Vascular-targeting activity of ZD6126, a novel tubulin-binding agent.
The tubulin-binding agent ZD6126 is a novel vascular-targeting agent in clinical development for the treatment of solid tumors… 
Highly Cited
2002
Highly Cited
2002
Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners.
An assay based on a solvent-sensitive fluorogenic dye molecule, badan, is used to test the binding affinity of a library of… 
Review
2002
Review
2002
Mechanisms of Ras Protein Targeting in Mammalian Cells
Many physiological and oncogenic activities of the 'classical' Ras proteins (H-Ras, N-Ras and K-Ras4A and -4B) require their… 
Highly Cited
2001
Highly Cited
2001
Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition.
Elastin-like polypeptides (ELPs) composed of a VPGXG repeat undergo a reversible phase transition in aqueous solution. They are… 
Highly Cited
1999
Highly Cited
1999
Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system.
The anticancer drug, adriamycin (ADR), was incorporated by physical entrapment into polymeric micelles for selective delivery to… 
Highly Cited
1993
Highly Cited
1993
Determination of the functional elements within the vacuolar targeting signal of barley lectin.
We have previously demonstrated that the carboxyl-terminal propeptide of barley lectin is both necessary and sufficient for… 
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