FAQ

cellular response to cisplatin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2015
01219972015

Papers overview

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2013
2013
Let-7b expression determines response to chemotherapy through the regulation of Cyclin D1 in Glioblastoma
BACKGROUND Glioblastoma is the most common type of primary brain tumors. Cisplatin is a commonly used chemotherapeutic agent for… (More)
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2013
2013
Suppression of Jab1/CSN5 induces radiation- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways
Nasopharyngeal carcinoma (NPC) is an Epstein–Barr virus-associated malignancy most common in East Asia and Africa. Radiotherapy… (More)
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2011
2011
Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells.
Cellular responses to DNA-damaging agents involve the activation of various DNA damage signaling and transduction pathways. Using… (More)
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2007
2007
Compromised Fanconi anemia response due to BRCA1 deficiency in cisplatin-sensitive head and neck cancer cell lines.
Head and neck cancers are commonly treated with the DNA-damaging agent cisplatin. While many tumors respond well to cisplatin… (More)
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2005
2005
Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta.
DNA polymerase beta (Pol beta) is an error-prone enzyme whose up-regulation has been shown to be a genetic instability enhancer… (More)
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Review
2004
Review
2004
Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review).
Cisplatin is one of the most potent anticancer agents, displaying significant clinical activity against a variety of solid tumors… (More)
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2004
2004
Global gene expression of fission yeast in response to cisplatin
The cellular response to the antitumor drug cisplatin is complex, and resistance is widespread. To gain insights into the global… (More)
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2000
2000
Molecular basis for resistance to the anticancer drug cisplatin in Dictyostelium.
The efficacy of the widely used chemotherapeutic drug cisplatin is limited by the occurrence of drug-resistant tumour cells. To… (More)
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2000
2000
Cisplatin-induced response of c-jun N-terminal kinase 1 and extracellular signal--regulated protein kinases 1 and 2 in a series of cisplatin-resistant ovarian carcinoma cell lines.
The cellular response to cisplatin involves activation of multiple signal transduction pathways, including the mitogen-activated… (More)
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Highly Cited
1999
Highly Cited
1999
Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
Many tumors overexpress mutant forms of p53. A growing number of studies suggest that the nature of a p53 mutation in a cell can… (More)
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