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cefoselis

Known as: (-)-5-Amino-2-(((6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-(2-hydroxyethyl)pyrazolium hydroxide, inner salt, 7(sup 2)-(Z)-(O-methyloxime), 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-, (6R-(6alpha,7beta(Z)))-, sulfate (salt) (1:1) 
A semisynthetic, broad-spectrum, beta-lactamase-resistant, fourth-generation cephalosporin with antibacterial activity. Cefoselis binds to and… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Anti-Bacterial AgentsCeftizoxime

Narrower (1)

FK 037
analogs & derivatives

Papers overview

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2013
2013
Preparation method of delta3 isomer of cefoselis
The invention provides a preparation method of a delta3 isomer of cefoselis in the field of compound preparation. The method… 
2012
2012
Analysis on utilization of cefoselis sulfate for injection in our hospital before and after intervention
Objective To evaluate the utilization of cefoselis sulfate for injection in our hospital before and after intervention.Methods… 
2011
2011
A multicenter study on the in vitro antibacterial activity of cefoselis against common clinical bacteria
Objective To evaluate the in vitro antibacterial activity of cefoselis against common clinical bacteria,including gram-positive… 
2011
2011
HPLC determination of cefoselis in human plasma
Objective: To establish a HPLC-UV method for determining concentration of cefoselis in human plasma.Methods:The sample was… 
2011
2011
Pharmacokinetics Study of Cefoselis Sulfate in Rabbits
OBJECTIVE:To study pharmacokinetics of cefoselis sulfate in rabbit.METHODS:15 rabbits were randomly divided into high-dose group… 
2011
2011
Clinical study of cefoselis in the treatment of acute lower respiratory tract infection
OBJECTIVE To evaluate the efficacy and safety of domestic Cefoselis in the treatment of patients with moderate to severe acute… 
2010
2010
A multicenter,double-blind,randomized controlled clinical trial of injectable cefoselis in the treatment of acute bacterial infections
Objective To evaluate the efficacy and safety of domestic injectable cefoselis in the treatment of acute bacterial infections… 
2010
2010
Preparation method of cefoselis sulfate
The invention discloses a preparation method of cefoselis sulfate and also discloses an important intermediate of 7beta… 
2009
2009
Clinical trial of cefoselis on community-acquired pneumonia.
Objective To evaluate the clinical efficacy and safety of injective cefoselis in the treatment of moderate to severe community… 
2008
2008
Cefoselis sulfate crystal and preparation method thereof
The invention relates to a cefoselis sulfate crystal and a preparation method thereof. The powder X-ray diffraction pattern of a…