FAQ

cefoselis

Known as: (-)-5-Amino-2-(((6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-(2-hydroxyethyl)pyrazolium hydroxide, inner salt, 7(sup 2)-(Z)-(O-methyloxime), 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-, (6R-(6alpha,7beta(Z)))-, sulfate (salt) (1:1) 
A semisynthetic, broad-spectrum, beta-lactamase-resistant, fourth-generation cephalosporin with antibacterial activity. Cefoselis binds to and… (More)

Topic mentions per year

Topic mentions per year

1995-2014
012319952014

Related topics

Related topics

3 relations

Broader (2)

Anti-Bacterial AgentsCeftizoxime

Narrower (1)

FK 037

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
cefoselis
Anti-Bacterial Agents
Ceftizoxime
FK 037

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1.
We examined the substrate specificity of human organic anion transporter (hOAT) 1 and hOAT3 for various cephalosporin antibiotics… (More)
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2003
2003
Evidence for the involvement of GABA(A) receptor blockade in convulsions induced by cephalosporins.
There is accumulating evidence that most beta-lactam antibiotics (i.e., cephalosporins and penicillins) have some degree of… (More)
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2002
2002
The beta-lactam antibiotics, penicillin-G and cefoselis have different mechanisms and sites of action at GABA(A) receptors.
The action of the beta-lactam antibiotics, penicillin-G (PCG) and cefoselis (CFSL) on GABA(A) receptors (GABA(A)-R) was… (More)
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2002
2002
Intracerebroventricular injection of the antibiotic cefoselis produces convulsion in mice via inhibition of GABA receptors.
A majority of beta-lactam antibiotics (e.g., cephalosporins and penicillins) have convulsive activity to a greater or lesser… (More)
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2002
2002
Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics.
In this study, we evaluated the current effectiveness of 11 beta-lactam antibiotics for treatment of orofacial odontogenic… (More)
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2001
2001
Effect of experimental renal failure on the pharmacodynamics of cefoselis-induced seizures in rats.
We investigated the effect of infusion rate and experimental renal failure on the pharmacodynamics of cefoselis (CFSL)-induced… (More)
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Highly Cited
2000
Highly Cited
2000
beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.
Therapeutic use of cephaloridine, a beta-lactam antibiotic, in humans is associated with carnitine deficiency. A potential… (More)
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2000
2000
[Clinical effects of cefoselis (CFSL) on infections in obstetric and gynecologic field and prevention of postoperative infections].
Clinical effects of cefoselis (CFSL) on various infections and prevention of postoperative infections in the field of obstetrics… (More)
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1996
1996
Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa.
Various Pseudomonas aeruginosa PAO1 NfxB mutants were isolated on agar plates containing cefpirome and ofloxacin. They were… (More)
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1995
1995
The Comparative In Vitro Activity of FK-037 (Cefoselis), a New Broad-Spectrum Cephalosporin.
FK-037, a new parenteral cephalosporin, was active against clinical isolates of both gram-positive and gram-negative aerobic… (More)
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