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cefoselis

Known as: (-)-5-Amino-2-(((6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-(2-hydroxyethyl)pyrazolium hydroxide, inner salt, 7(sup 2)-(Z)-(O-methyloxime), 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-, (6R-(6alpha,7beta(Z)))-, sulfate (salt) (1:1) 
A semisynthetic, broad-spectrum, beta-lactamase-resistant, fourth-generation cephalosporin with antibacterial activity. Cefoselis binds to and… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Anti-Bacterial AgentsCeftizoxime

Narrower (1)

FK 037
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Multicenter, double-blind, randomized clinical trial of parenterally administered Cefoselis versus Cefepime for the treatment of acute bacterial infections.
AIM This study aims to evaluate the clinical efficacy and safety of intravenous Cefoselis injection for the treatment of acute… 
2013
2013
Preparation method of delta3 isomer of cefoselis
The invention provides a preparation method of a delta3 isomer of cefoselis in the field of compound preparation. The method… 
2011
2011
A multicenter study on the in vitro antibacterial activity of cefoselis against common clinical bacteria
Objective To evaluate the in vitro antibacterial activity of cefoselis against common clinical bacteria,including gram-positive… 
2009
2009
Pharmacokinetics of cefoselis injection after a single dose in Chinese healthy volunteers
  • Zhu Xu
  • 2009
  • Corpus ID: 102042456
Objective To investigate the pharmacokinetics of a single dose cefoselis sulfate injection in Chinese healthy volunteers.Methods… 
2002
2002
The β-lactam antibiotics,penicillin-G and cefoselis have different mechanisms and sites of action at GABAA receptors
2001
2001
Effect of experimental renal failure on the pharmacodynamics of cefoselis-induced seizures in rats.
We investigated the effect of infusion rate and experimental renal failure on the pharmacodynamics of cefoselis (CFSL)-induced… 
2000
2000
[Clinical effects of cefoselis (CFSL) on infections in obstetric and gynecologic field and prevention of postoperative infections].
Clinical effects of cefoselis (CFSL) on various infections and prevention of postoperative infections in the field of obstetrics… 
2000
2000
In-vitro activity of FK 037 (Cefoselis), a novel 4(th) generation cephalosporin, compared to cefepime and cefpirome on nosocomial staphylococci and gram-negative isolates.
Review
1996
Review
1996
Tissue penetration of the fourth generation parenteral cephalosporins.
In this review, the methods employed to study tissue penetration are discussed. Mathematical, animal and human models all have… 
1996
1996
Newer antipseudomonal cephalosporins.
The in vitro antipseudomonal activity of eight cephalosporins with alpha-oxyimino-aminothiazolyl or aminothiadiazolyl group in… 
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