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cefepime

Known as: Cefepima, cefepim, cefepime [Chemical/Ingredient] 
A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding… Expand
National Institutes of Health

Related topics

Related topics

32 relations
Acinetobacter InfectionsBacterial InfectionsBone Diseases, InfectiousCefepime Islt KB
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Broader (1)

Anti-Bacterial Agents

Narrower (3)

BMY 28142MaxipimeQuadrocef

Papers overview

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Highly Cited
2014
Highly Cited
2014
Comparison of Acute Kidney Injury During Treatment with Vancomycin in Combination with Piperacillin‐Tazobactam or Cefepime
To evaluate the observed incidence of acute kidney injury (AKI) in adult patients receiving either piperacillin‐tazobactam and… Expand
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Highly Cited
2013
Highly Cited
2013
Cefepime therapy for monomicrobial bacteremia caused by cefepime-susceptible extended-spectrum beta-lactamase-producing Enterobacteriaceae: MIC matters.
BACKGROUND Extended-spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae isolates are important clinical pathogens. In… Expand
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Highly Cited
2008
Highly Cited
2008
Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections.
The objective of this study was to evaluate the relationship of the predicted pharmacodynamic parameters 24-h area under the… Expand
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Highly Cited
2005
Highly Cited
2005
Emergence of Daptomycin Resistance in Enterococcus faecium during Daptomycin Therapy
Daptomycin is a cyclic lipopeptide antibiotic that has been available in the United States since September 2003. We report a… Expand
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Highly Cited
2003
Highly Cited
2003
Cefepime versus Imipenem-Cilastatin for Treatment of Nosocomial Pneumonia in Intensive Care Unit Patients: a Multicenter, Evaluator-Blind, Prospective, Randomized Study
ABSTRACT In a randomized, evaluator-blind, multicenter trial, we compared cefepime (2 g three times a day) with imipenem… Expand
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Highly Cited
2002
Highly Cited
2002
Detection of Plasmid-Mediated AmpC β-Lactamase Genes in Clinical Isolates by Using Multiplex PCR
ABSTRACT Therapeutic options for infections caused by gram-negative organisms expressing plasmid-mediated AmpC β-lactamases are… Expand
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Highly Cited
2002
Highly Cited
2002
Pharmacodynamics of cefepime in patients with Gram-negative infections.
We conducted a prospective, open-label study to delineate a relationship between exposure and outcomes in 36 patients treated… Expand
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Highly Cited
2001
Highly Cited
2001
Cefepime, Piperacillin-Tazobactam, and the Inoculum Effect in Tests with Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae
ABSTRACT There is little information about the clinical effectiveness of cefepime and piperacillin-tazobactam in the treatment of… Expand
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Highly Cited
2000
Highly Cited
2000
Characterization of VIM-2, a Carbapenem-Hydrolyzing Metallo-β-Lactamase and Its Plasmid- and Integron-Borne Gene from a Pseudomonas aeruginosa Clinical Isolate in France
ABSTRACT Pseudomonas aeruginosa COL-1 was identified in a blood culture of a 39-year-old-woman treated with imipenem in… Expand
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Highly Cited
1999
Highly Cited
1999
Cloning and Characterization of blaVIM, a New Integron-Borne Metallo-β-Lactamase Gene from a Pseudomonas aeruginosa Clinical Isolate
ABSTRACT Production of a metallo-β-lactamase activity was detected in a carbapenem-resistant Pseudomonas aeruginosa clinical… Expand
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