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carvedilol

Known as: (+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol, Carvedilolum, carvedilol [Chemical/Ingredient] 
A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta… 
National Institutes of Health

Related topics

Related topics

31 relations
24 HR carvedilol phosphate 20 MG Extended Release Oral Capsule24 HR carvedilol phosphate 80 MG Extended Release Oral Capsule [Coreg]Adrenergic alpha-Antagonists [MoA]Angina Pectoris

Broader (6)

Adrenergic alpha-1 Receptor AntagonistsAdrenergic beta-AntagonistsAntihypertensive AgentsCarbazoles

Narrower (2)

Coregcarvedilol hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
A pilot study on the role of autoantibody targeting the beta1-adrenergic receptor in the response to beta-blocker therapy for congestive heart failure.
Highly Cited
2008
Highly Cited
2008
Intracellular mechanisms of specific beta-adrenoceptor antagonists involved in improved cardiac function and survival in a genetic model of heart failure.
2006
2006
Multiple regression analysis of pharmacogenetic variability of carvedilol disposition in 54 healthy Japanese volunteers.
The aim of this study was to evaluate the pharmacogenetic variability in the disposition of carvedilol in the Japanese population… 
Highly Cited
2005
Highly Cited
2005
Sympathetic modulation by carvedilol and losartan reduces angiotensin II-mediated lipolysis in subcutaneous and visceral fat.
Advanced heart failure is characterized by increased activation of the renin-angiotensin system and the development of cachexia… 
2005
2005
New positron emission tomography tracer [11C]carvedilol reveals P‐glycoprotein modulation kinetics
1 Imaging of P‐glycoprotein (P‐gp) function in the blood–brain barrier (BBB) may support development of strategies, which will… 
Highly Cited
2000
Highly Cited
2000
Improvement of cardiac neuronal function after carvedilol treatment in dilated cardiomyopathy: a 123I-MIBG scintigraphic study.
UNLABELLED Carvedilol can induce important clinical and hemodynamic improvements in patients with chronic heart failure resulting… 
1998
1998
Metabolism of carvedilol in dogs, rats, and mice.
The excretion and biotransformation of carvedilol [1-[carbazolyl-(4)-oxy]-3-[(2-methoxyphenoxyethyl)amino]-2-p ropanol], a new… 
Review
1997
Review
1997
Effects of beta-adrenergic blockade on survival of patients with chronic heart failure.
Highly Cited
1997
Highly Cited
1997
Nonselective β-Adrenergic Blockade With Carvedilol Does Not Hinder the Benefits of Exercise Training in Patients With Congestive Heart Failure
Background Long-term β-adrenergic blockade does not appear to be associated with drug-induced training in patients with… 
1996
1996
Different response of the rat left and right heart to norepinephrine.
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