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carolacton

 
National Institutes of Health

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2017
2017
The natural product carolacton is a macrolide keto-carboxylic acid produced by the myxobacterium Sorangium cellulosum, and was… Expand
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2017
2017
The oral microbiome is a dynamic environment inhabited by both commensals and pathogens. Among these is Streptococcus mutans, the… Expand
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2017
2017
A short and convergent strategy for the stereoselective total synthesis of biologically active natural product carolacton has… Expand
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2016
2016
New antibacterial compounds, preferentially exploiting novel cellular targets, are urgently needed to fight the increasing… Expand
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2015
2015
Carolacton, a secondary metabolite isolated from the extracts of Sorangium cellulosum, causes membrane damage and cell death in… Expand
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2013
2013
OBJECTIVE Caries adjacent to restorations is one of the main causes for restoration replacement. Antimicrobial substances… Expand
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2013
2013
BackgroundCarolacton is a newly identified secondary metabolite causing altered cell morphology and death of Streptococcus mutans… Expand
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2012
2012
in biofilms at nanomolar concentration. In particular, biofilms containing the cariesand endocarditis-associated bacterium… Expand
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2011
2011
Carolacton, a secondary metabolite isolated from the myxobacterium Sorangium cellulosum, disturbs Streptococcus mutans biofilm… Expand
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2010
2010
BackgroundStreptococcus mutans is a major pathogen in human dental caries. One of its important virulence properties is the… Expand
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