cardiovascular pharmacology

Selective inhibitors of cyclooxygenase (COX)-2, the coxibs, were developed to inhibit inflammatory prostaglandins derived from… (More)

A wide range of drugs has been shown to prolong the QT interval of the electrocardiogram by blocking the pore-forming subunit of… (More)

We characterized the in vivo cardiovascular profile of SCH 58261, 7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2, 4… (More)

Medetomidine was administered to sheep and horses at a dose rate of 5 microg kg(-1) (i.v.). Heart rate and blood pressure were… (More)

The history of cardiology encompasses some of the most revered names in medical history, many belonging to physicians who have… (More)

Dose-response infusions (0.25 to 4.0 micrograms/kg/min) and extended infusions of dopexamine, a new synthetic catechol with beta… (More)

The haemodynamic, antianginal and antihypertensive effects of nicardipine, a vascular selective calcium antagonist, were studied… (More)

We evaluated the acute hemodynamic effects of doxorubicin in the open-chest dog. Doxorubicin at doses of 1-4 mg/kg administered… (More)

The mechanism of action of prazosin hydrochloride, a new antihypertensive agent was studied in 14 patients with essential… (More)

The success of propranolol in treating the symptoms of angina pectoris has raised questions about the effects of beta-adrenergic… (More)