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calfactant

Known as: Calf lung surfactant extract (CLSE), calfactant [Chemical/Ingredient] 
A sterile suspension composed of an extract of bovine pulmonary surfactant with surfactant activity. Calfactant contains phospholipids, neutral… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Biological ProductsPulmonary Surfactants

Narrower (2)

Infasurfcalfactant 35 MG/ML Intratracheal Suspension [Infasurf]
Surfactant Activity [MoA]beractant 25 MG/ML Intratracheal Suspension [Survanta]

Papers overview

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Highly Cited
2016
Highly Cited
2016
Randomized trial of laryngeal mask airway versus endotracheal intubation for surfactant delivery
Objective:To compare the effectiveness of surfactant delivery via endotracheal tube (ETT) using an intubation-surfactant-rapid… 
Highly Cited
2013
Highly Cited
2013
Pediatric Calfactant in Acute Respiratory Distress Syndrome Trial*
Rationale: Our previous studies in children with acute lung injury/acute respiratory distress syndrome demonstrated improved… 
Review
2013
Review
2013
Medication Use in the Neonatal Intensive Care Unit
Abstract Objective The aim of the article is to provide an update on medication use in infants admitted to the neonatal intensive… 
Highly Cited
2013
Highly Cited
2013
The Relationship of Fluid Administration to Outcome in the Pediatric Calfactant in Acute Respiratory Distress Syndrome Trial*
Objectives: Adult studies have demonstrated the relationship between fluid overload and poor outcomes in acute lung injury/acute… 
Review
2011
Review
2011
Efficacy of Porcine Versus Bovine Surfactants for Preterm Newborns With Respiratory Distress Syndrome: Systematic Review and Meta-analysis
OBJECTIVE: To compare the efficacy of a porcine surfactant (poractant alfa) versus bovine surfactants (beractant and calfactant… 
Review
2005
Review
2005
Comparison of Infasurf (Calfactant) and Survanta (Beractant) in the Prevention and Treatment of Respiratory Distress Syndrome
Background. In biophysical and animal testing, Infasurf develops lower surface tension and restores total surfactant activity… 
Highly Cited
1999
Highly Cited
1999
Instillation of calf lung surfactant extract (calfactant) is beneficial in pediatric acute hypoxemic respiratory failure. Members of the Mid-Atlantic Pediatric Critical Care Network.
OBJECTIVE Prospective study of the efficacy of calf lung surfactant extract in pediatric respiratory failure. DESIGN Multi… 
Highly Cited
1995
Highly Cited
1995
Pulmonary surfactant maintains patency of conducting airways in the rat.
The hypothesis was tested that after extrusion of the liquid columns that often block the lumen of conducting airways, the latter… 
Highly Cited
1992
Highly Cited
1992
High‐frequency jet ventilation and surfactant treatment of newborns with severe respiratory failure
Twenty‐eight newborn infants (birthweight, 2.4 ± 1.1 kg; gestational age, 34.6 ± 6.1 weeks) with respiratory distress syndrome… 
Highly Cited
1987
Highly Cited
1987
Mitigation of pulmonary hyperoxic injury by administration of exogenous surfactant.
We studied the effects of surfactant supplementation on the progression of lung injury in rabbits exposed to 100% O2 for 64 h and… 
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