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cadeguomycin

Known as: 1H-Pyrrolo(2,3-d)pyrimidine-5-carboxylic acid, 2-amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-, 2-amino-3,4-dihydro-4-oxo-7-beta-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-carboxylic acid, 7-carboxy-7-deazaguanosine 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Guanosine
analogs & derivatives

Papers overview

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2006
2006
ENHANCEMENT OF PYRIMIDINE K562 AND YAC-1 CELLS NUCLEOSIDE UPTAKE INTO BY CADEGUOMYCIN
Cadeguomycin markedly stimulated the uptake of thymidine, deoxycytidine and uridine into the acid-insoluble fraction of K562… 
1991
1991
Structure-activity relationships of cadeguomycin analogs.
The relationship between the activity and the chemical structure of cadeguomycin (CDM, 7-carboxy-7-deazaguanosine) was studied… 
1990
1990
[Antitumor drugs and potentiators aiming circumvention of drug resistance].
We have been studying the resistance mechanisms of various antitumor drugs and screening substances from natural and synthetic… 
1989
1989
Nucleoside peptides. 10. Synthesis and T-cell immunostimulatory properties of certain peptide derivatives of 6-azacadeguomycin.
Several amino acid and peptide conjugates of 6-azacadeguomycin (6-amino-1-beta-D-ribofuranosyl-4,5-dihydro-4-oxopyrazolo[3,4-d]py… 
1987
1987
Potentiation of cytotoxicity of 1-beta-D-arabinofuranosylcytosine for K562 human leukemic cells by cadeguomycin.
The treatment of K562 human myeloblastic leukemia cells and YAC-1 murine lymphoma cells with cadeguomycin at concentrations over… 
1987
1987
Effects of cadeguomycin on cytotoxicity of cytosine arabinoside and other pyrimidine nucleoside analogs; a comparative study.
than 25 ^g/ml), it strongly potentiates cytotoxicity of 1 -^-D-arabinofuranosylcytosine (AraC) against K562 cells by increasing… 
1985
1985
Biological activity of cadeguomycin. Inhibition of tumor growth and metastasis, immunostimulation, and potentiation of 1-beta-D-arabinofuranosylcytosine.
Cadeguomycin retarded growth of sc solid IMC carcinoma in CDF1 mice, and pulmonary metastasis of Lewis lung carcinoma in C57BL/6… 
1983
1983
Pyrrolopyrimidine nucleosides 19. A total synthesis of the nucleoside antibiotic cadeguomycin [2-amino-7-(β-d-ribofuranosyl)-pyrrolo[2,3-d]pyrimidin-4-one-5-carboxylic acid]☆
Review
1983
Review
1983
[Study of new antineoplastic antibiotics based on newly discovered action mechanisms].
In our laboratory, we have studied the mechanism of action of tumor-inhibitory antibiotics, including bleomycin, phleomycin… 
1982
1982
Cadeguomycin, a noval nucleoside analog antibiotic. I. The producing organism, production and isolation of cadeguomycin.
An actinomycete strain IM7912T was found to produce cadeguomycin, a new nucleoside analog antibiotic, together with tubercidin… 
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