cGMP catabolic process

Known as: cGMP breakdown, cGMP catabolism, cGMP degradation 
The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate. [GOC:go_curators]

Topic mentions per year

Topic mentions per year

1979-2018
051019792018

Papers overview

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2008
2008
We recently demonstrated early metabolic alterations in the dystrophin-deficient mdx heart that precede overt cardiomyopathy and… (More)
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2004
2004
Sildenafil, tadalafil, and vardenafil each competitively inhibit cGMP hydrolysis by phosphodiesterase-5 (PDE5), thereby fostering… (More)
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2004
2004
AIMS To examine the hypothesis that sildenafil, a phosphodiesterase type 5 inhibitor that inhibits cGMP breakdown, could enhance… (More)
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Highly Cited
2003
Highly Cited
2003
In platelets, the nitric oxide (NO)-induced cGMP response is indicative of a highly regulated interplay of cGMP formation and… (More)
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2002
2002
In an attempt to elaborate in vitro on a therapeutic strategy that counteracts an inflammatory signal, we previously reported a… (More)
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2001
2001
Most of the effects of the signaling molecule nitric oxide (NO) are mediated by cGMP, which is synthesized by soluble guanylyl… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVES To determine the acute effects of type 5 phosphodiesterase inhibition with sildenafil on flow-mediated vasodilation in… (More)
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2000
2000
A major receptor for nitric oxide (NO) is the cGMP-synthesizing enzyme, soluble guanylyl cyclase (sGC), but it is not known how… (More)
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1997
1997
Although guanosine 3',5'-cyclic monophosphate (cGMP) acts as a relaxant second messenger, the regulation of intracellular cGMP… (More)
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1996
1996
Regulation of endothelial permeability is poorly understood. Previous studies have shown that endothelial cells contain… (More)
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