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brimonidine

Known as: Brimodine, Brimonidina, 5-bromo-6-(imidazolin-2-ylamino)quinoxaline 
An imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine acts on the blood vessels… 
National Institutes of Health

Related topics

Related topics

11 relations
Adrenergic alpha2-Agonists [MoA]Brimonidine tartrate 1.5 MG/ML Ophthalmic Solution [Alphagan]Drug AllergyGlaucoma, Open-Angle

Narrower (5)

AlphaganBrimonidine tartrateCombiganMirvaso

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Cellular Cytotoxicity of Antiglaucoma Drugs in Cultured Corneal Endothelial Cells
2006
2006
Characterization of brimonidine transport in retinal pigment epithelium.
PURPOSE To investigate the involvement of carrier-mediated transport mechanisms in brimonidine transport in retinal pigment… 
Highly Cited
2005
Highly Cited
2005
Ischemia results 3 months later in altered ERG, degeneration of inner layers, and deafferented tectum: neuroprotection with brimonidine.
PURPOSE To investigate the long-term effects of transient ligature of the ophthalmic vessels (LOV) on the inner and outer retina… 
2004
2004
Comparative study of the effects of desipramine and reboxetine on locus coeruleus neurons in rat brain slices
2003
2003
Efficacy and safety of timolol maleate/latanoprost fixed combination versus timolol maleate and brimonidine given twice daily.
PURPOSE To evaluate the efficacy and safety of the timolol maleate/latanoprost fixed combination (TLFC) given once each evening… 
2001
2001
Effectiveness and Safety of Brimonidine as Adjunctive Therapy for Patients With Elevated Intraocular Pressure in a Large, Open-label Community Trial
PurposeTo determine the effectiveness and safety of brimonidine when used in combination with one or more glaucoma medications in… 
1994
1994
Apraclonidine and brimonidine effects on anterior ocular and cardiovascular physiology in normal and sympathectomized monkeys.
Apraclonidine and brimonidine administered topically to one eye of ketamine-anesthetized normal cynomolgus monkeys each produced… 
1994
1994
Alpha 2-adrenoceptor-mediated inhibition of electrically evoked [3H]noradrenaline release from chick sympathetic neurons: role of cyclic AMP.
This study explores the role of cyclic AMP in electrically evoked [3H]noradrenaline release and in the alpha 2-adrenergic… 
1993
1993
Neural ATP release and its α2-adrenoceptor-mediated modulation in guinea-pig vas deferens
SummaryContractions, release of previously stored [3H]-noradrenaline (measured as overflow of total tritiated compounds) and… 
1993
1993
Presynaptic α2-autoreceptors in brain cortex: α2D in the rat and α2A in the rabbit
SummaryPresynaptic α2-autoreceptors in rat and rabbit brain cortex were compared by means of antagonists and agonists. Brain… 
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