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brevican
Known as:
Brain-Enriched Hyaluronan-Binding Protein
, Chondroitin Sulfate Proteoglycan 7
, Brain Enriched Hyaluronan Binding Protein
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A BRAIN-specific hyalectin that may play a role in terminally differentiating NEURONS. It is found highly overexpressed in primary BRAIN TUMORS and…
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National Institutes of Health
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Related topics
Related topics
10 relations
BCAN gene
In Blood
Process of secretion
agonists
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Narrower (1)
BCAN protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
The role of brevican in glioma: promoting tumor cell motility in vitro and in vivo
R. Lu
,
Chengsheng Wu
,
+6 authors
Min Yu
BMC Cancer
2012
Corpus ID: 9674173
BackgroundMalignant glioma is a common primary tumor of the central nervous system. Brevican, an abundant extracellular matrix…
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Highly Cited
2008
Highly Cited
2008
The Proteoglycan Brevican Binds to Fibronectin after Proteolytic Cleavage and Promotes Glioma Cell Motility*
Bin Hu
,
L. Kong
,
R. T. Matthews
,
M. Viapiano
Journal of Biological Chemistry
2008
Corpus ID: 35779518
The adult neural parenchyma contains a distinctive extracellular matrix that acts as a barrier to cell and neurite motility…
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Highly Cited
2003
Highly Cited
2003
The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury
L. Jones
,
R. U. Margolis
,
M. Tuszynski
Experimental Neurology
2003
Corpus ID: 16748373
Highly Cited
2002
Highly Cited
2002
Brevican-Deficient Mice Display Impaired Hippocampal CA1 Long-Term Potentiation but Show No Obvious Deficits in Learning and Memory
C. Brakebusch
,
C. Seidenbecher
,
+10 authors
R. Fässler
Molecular and Cellular Biology
2002
Corpus ID: 2621716
ABSTRACT Brevican is a brain-specific proteoglycan which is found in specialized extracellular matrix structures called…
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Highly Cited
2000
Highly Cited
2000
Brain-enriched Hyaluronan Binding (BEHAB)/Brevican Cleavage in a Glioma Cell Line Is Mediated by a Disintegrin and Metalloproteinase with Thrombospondin Motifs (ADAMTS) Family Member*
R. T. Matthews
,
S. C. Gary
,
+4 authors
S. Hockfield
The Journal of Biological Chemistry
2000
Corpus ID: 39750981
Brain-enriched hyaluronan binding (BEHAB)/brevican is a brain-specific extracellular matrix protein containing a cleavage site…
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Highly Cited
2000
Highly Cited
2000
Brevican Is Degraded by Matrix Metalloproteinases and Aggrecanase-1 (ADAMTS4) at Different Sites*
Hiroyuki Nakamura
,
Y. Fujii
,
+6 authors
Y. Okada
The Journal of Biological Chemistry
2000
Corpus ID: 45323016
Brevican is a member of the lectican family of chondroitin sulfate proteoglycans that is predominantly expressed in the central…
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Highly Cited
1998
Highly Cited
1998
Differential regulation of expression of hyaluronan-binding proteoglycans in developing brain: aggrecan, versican, neurocan, and brevican.
P. Milev
,
P. Maurel
,
+5 authors
R. U. Margolis
Biochemical and biophysical research…
1998
Corpus ID: 29976083
We have used a slot-blot radioimmunoassay to quantitate the levels of hyaluronan-binding chondroitin sulfate proteoglycans in…
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Highly Cited
1997
Highly Cited
1997
The Brain Chondroitin Sulfate Proteoglycan Brevican Associates with Astrocytes Ensheathing Cerebellar Glomeruli and Inhibits Neurite Outgrowth from Granule Neurons
Hidekazu Yamada
,
B. Fredette
,
+5 authors
Y. Yamaguchi
The Journal of Neuroscience
1997
Corpus ID: 255942
Brevican is a nervous system-specific chondroitin sulfate proteoglycan that belongs to the aggrecan family and is one of the most…
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Highly Cited
1995
Highly Cited
1995
Brevican, a Chondroitin Sulfate Proteoglycan of Rat Brain, Occurs as Secreted and Cell Surface Glycosylphosphatidylinositol-anchored Isoforms (*)
C. Seidenbecher
,
K. Richter
,
U. Rauch
,
R. Fässler
,
C. Garner
,
E. Gundelfinger
The Journal of Biological Chemistry
1995
Corpus ID: 35453291
cDNA clones encoding proteins related to the aggrecan/versican family of proteoglycan core proteins have been isolated with…
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Highly Cited
1994
Highly Cited
1994
Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family.
H. Yamada
,
K. Watanabe
,
M. Shimonaka
,
Y. Yamaguchi
The Journal of biological chemistry
1994
Corpus ID: 33433459
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