brazilin

Known as: brasilin 
 
National Institutes of Health

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Benzopyrans

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2015
2015
Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
Soluble amyloid β-protein (Aβ) oligomers, the main neurotoxic species, are predominantly formed from monomers through a fibril… (More)
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2013
2013
Brazilin Inhibits Growth and Induces Apoptosis in Human Glioblastoma Cells
Brazilin, isolated from the methanol extract of the heart wood of Caesalpinia sappan, sensitizes cancer cells to apoptosis… (More)
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2012
2012
Brazilin induces apoptosis and G2/M arrest via inactivation of histone deacetylase in multiple myeloma U266 cells.
Although brazilin [7,11b-dihydrobenz(b)indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol] isolated from Caesalpinia sappan was known to… (More)
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2009
2009
Brazilin from Caesalpinia sappan wood as an antiacne agent
In screening experiments for antiacne activity, methanolic and 50% ethanolic extracts of Caesalpinia sappan wood showed the most… (More)
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2009
2009
Heme oxygenase-1 mediates the inhibitory actions of brazilin in RAW264.7 macrophages stimulated with lipopolysaccharide.
Brazilin, the main constituent of Caesalpinia sappan L., is a natural red pigment that has been reported to possess anti… (More)
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2008
2008
Upregulation of heme oxygenase-1 by brazilin via the phosphatidylinositol 3-kinase/Akt and ERK pathways and its protective effect against oxidative injury.
Heme oxygenase (HO)-1 is a cytoprotective enzyme that is activated by various phytochemicals. We examined the ability of brazilin… (More)
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2005
2005
Suppression of lipopolysaccharide-induced expression of inducible nitric oxide synthase by brazilin in RAW 264.7 macrophage cells.
Brazilin (7,11b-dihydrobenz[b]indeno[1,2-d]pyran-3,6a,9,10 (6H)-tetrol) isolated from Caesalpinia sappan has been known as a… (More)
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2003
2003
Induction of vasorelaxation through activation of nitric oxide synthase in endothelial cells by brazilin.
The vasorelaxant activity of Caesalpinia sappan L., a traditional Chinese medicine, and its major component brazilin were… (More)
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1997
1997
Brazilin modulates immune function mainly by augmenting T cell activity in halothane administered mice.
Previously we reported that brazilin, the main principle of Caesalpinia sappan, was able to improve the altered immune functions… (More)
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1992
1992
Brazilin protects cultured rat hepatocytes from BrCCl3-induced toxicity.
Brazilin, the main constituent of Caesalpinia sappan, is an antioxidative substance that has catechol moiety in its chemical… (More)
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