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The epithelial–mesenchymal transition (EMT) is a phenomenon that facilitates epithelial cells to acquire invasive potential to… Expand Persistent phosphorylation of signal transducers and activators of transcription 3 (STAT3) is frequently observed in tumor cells… Expand Proliferation is an important part of cancer development and progression. This is manifest by altered expression and/or activity… Expand Botanical and nutritional compounds have been used for the treatment of cancer throughout history. These compounds also may be… Expand Agents that interfere with tumoral immune tolerance may be useful to prevent or treat cancer. Brassinin is a phytoalexin, a class… Expand A screen of indole-based structures revealed the natural product brassinin to be a moderate inhibitor of indoleamine 2,3… Expand Brassinin (1), a crucial plant defense produced by crucifers, is detoxified by the phytopathogenic fungus Leptosphaeria maculans… Expand Botanicals have been used for the treatment of various human diseases throughout history. In addition, botanicals play a role in… Expand The phytoalexins, brassinin, 1-methoxybrassinin and cyclobrassinin, were metabolized by the stem rot fungus Sclerotinia… Expand Brassinin [3-(S-methyldithiocarbamoyl)aminomethyl indole], a phytoalexin first identified as a constituent of cabbage, was… Expand