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biotinidase activity

Known as: amidohydrolase biotinidase activity, biotin-amide amidohydrolase activity 
Catalysis of the reaction: biotin amide + H2O = biotin + NH3. [EC:3.5.1.12, MetaCyc:BIOTINIDASE-RXN]
National Institutes of Health

Papers overview

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2009
2009
Some of the side effects that develop during long-term valproic acid (VPA) treatment are similar to symptoms of zinc and partial… Expand
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2004
2004
Biotinidase deficiency is an inherited metabolic disorder characterized by neurological and cutaneous symptoms. Fortunately, it… Expand
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Highly Cited
2001
Highly Cited
2001
Summary:  Purpose: Valproic acid (VPA) is an effective antiepileptic drug (AED), which is associated with dose‐related adverse… Expand
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1997
1997
As part of our development of antibody pretargeting for cancer therapy, an investigation has been conducted to examine the… Expand
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1993
1993
To investigate whether biotinidase deficiency may occur in liver disease, we determined biotinidase activity, biotin levels, and… Expand
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Highly Cited
1990
Highly Cited
1990
Between January 24, 1984, and December 31, 1988, 29 screening programs for biotinidase deficiency in newborns were established in… Expand
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1987
1987
A simple and reliable method for quantification of biotinidase (EC.3.5.1.12) activity in dried blood spot was devised by a… Expand
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Highly Cited
1985
Highly Cited
1985
We have developed a method for rapid differential diagnosis of isolated or multiple deficiencies of the 3 mitochondrial biotin… Expand
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1983
1983
A new, sensitive radioassay for the determination of biotinidase activity was developed which measures the release of [14C… Expand
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1963
1963
Korvusalo, M. and J. Pispa. Biotinidase activity in animal tissues. Acta physiol. scand. 1963. 58. 13—19. — Biotinidase activity… Expand
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