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biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity

Known as: biotin-propionyl coenzyme A carboxylase synthetase activity, holocarboxylase synthetase activity, propionyl-CoA holocarboxylase synthetase activity 
Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl… 
National Institutes of Health

Papers overview

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2018
2018
GlnR-Mediated Regulation of Short-Chain Fatty Acid Assimilation in Mycobacterium smegmatis
Assimilation of short-chain fatty acids (SCFAs) plays an important role in the survival and lipid biosynthesis of Mycobacteria… 
2011
2011
A 96-well plate assay for high-throughput analysis of holocarboxylase synthetase activity.
2011
2011
Characterization of human holocarboxylase synthetase activity and specificity
1998
1998
Deficiency of biotinyl-AMP synthetase activity in fibroblasts of patients with holocarboxylase synthetase deficiency.
A simple, rapid assay was developed to diagnose holocarboxylase synthetase deficiency. Holocarboxylase synthetase first catalyzes… 
1996
1996
Protein biotinylation in higher plants: characterization of biotin holocarboxylase synthetase activity from pea (Pisum sativum) leaves.
Biotin holocarboxylase synthetase was partially purified from pea leaves by a sequence of ammonium sulphate fractionation and… 
1983
1983
Regulation and intracellular localization of the biotin holocarboxylase synthetase of 3T3-L1 cells.
Highly Cited
1982
Highly Cited
1982
Evidence for a defect of holocarboxylase synthetase activity in cultured lymphoblasts from a patient with biotin-responsive multiple carboxylase deficiency.
We report here the expression of biotin-responsive multiple carboxylase deficiency in cultured lymphoblasts of a patient whose… 
1982
1982
Search for the biochemical basis of biotin dependent multiple carboxylase deficiencies: determination of biotin activation in cultured fibroblasts.
Highly Cited
1981
Highly Cited
1981
Mutant holocarboxylase synthetase: evidence for the enzyme defect in early infantile biotin-responsive multiple carboxylase deficiency.
Biotin-responsive multiple carboxylase deficiency is an inherited disorder of organic acid metabolism in man in which there are… 
1966
1966
Carboxylation of crotonyl-CoA by mammalian enzyme systems.
In a crude dialyzed ammonium sulfate fraction (35–65% saturation) of rat liver, carbon dioxide fixation into crotonyl-CoA took… 
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