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benfluron

Known as: 5-(2-dimethylaminoethoxy)-7-oxo-7H-benzo(c)fluorene, benflurone 
National Institutes of Health

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VUFB 13468

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1998
1998
Induction and Inhibition of Cytochrome P450-Catalysed Reduction of Biologically Active Benfluron N-Oxide
Benfluron N-oxide [5-(2-N-oxo-2-N,N'-dimethylaminoethoxy)-7-oxo-7-H-benzo[c]fluorene] is a biologically active substance which… 
1993
1993
9‐Hydroxybenfluron induced inhibition of proliferation and metabolism in hela cells
The highest concentration of 9‐hydroxybenfluron (HBF) tested, namely 4·05 μmol1−1, induced immediate cytotoxic effects which were… 
1991
1991
Elimination of Benfluron and its Metabolites in the Faeces and Urine of Rats
The study of the biotransformation of the potential cytostatic benfluron has been continued. The elimination of benfluron and of… 
1990
1990
Evaluation of photometric high-performance liquid chromatographic data for the determination of benflurone metabolites in biological materials with and without concomitant use of a standard.
1989
1989
Effect of benfluron metabolites on ATP level in tumor cells.
Changes in ATP levels of both Ehrlich ascites carcinoma and P388 leukemia cells were evaluated after 2 h of incubation in the… 
1989
1989
Effects of benfluron metabolites on glycolysis and level of thiol groups in P388 and Ehrlich ascites cells.
The effects of two benfluron metabolites, namely 7-dihydrobenfluron (DBF) and N-oxide of benfluron (NOBF), on the aerobic… 
1988
1988
HEMA-particles phagocytosis of rat neutrophils.
  • J. Berger
  • Folia haematologica
  • 1988
  • Corpus ID: 35275179
A micromethod for testing of phagocytosis employing synthetic hydrophilic HEMA particles seems to be suitable for an examination… 
1987
1987
Chromatographic and enzymatic evidence for the structure of an oxygenated and reduced metabolite of Benflurone.
1985
1985
Derivatives of benzo(c)fluorene. XVI. Absorption, distribution and elimination of 3H-benflurone, 5-(2-N,N-dimethylamino)ethoxy)-7-oxo-7H-benzo(c)fluorene hydrochloride in rats after oral and…
3H-benfluorone administered orally to rats, persists for a long time in the stomach; it is absorbed only partly and eliminated… 
1984
1984
Chromatographic characterization of in vitro metabolites of 5-[2-(N,N-dimethylamino)ethoxy]-7-oxo-7H-benzo[c]fluorene.
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