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batabulin

Known as: 2-Fluoro-1-methoxy-4-pentafluorophenylsulfonamidobenzene 
A synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. Batabulin covalently binds to beta tubulin, resulting in a… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Microtubule Process

Broader (1)

Sulfonamides

Narrower (1)

T 138067

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Selective, covalent modification of beta-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumors.
Microtubules are linear polymers of alpha- and beta-tubulin heterodimers and are the major constituents of mitotic spindles… Expand
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