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batabulin
Known as:
2-Fluoro-1-methoxy-4-pentafluorophenylsulfonamidobenzene
A synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. Batabulin covalently binds to beta tubulin, resulting in a…
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National Institutes of Health
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Related topics
Related topics
3 relations
Microtubule Process
Broader (1)
Sulfonamides
Narrower (1)
T 138067
Papers overview
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Highly Cited
1999
Highly Cited
1999
Selective, covalent modification of beta-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumors.
B. Shan
,
J. Medina
,
+10 authors
H. Beckmann
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 27520086
Microtubules are linear polymers of alpha- and beta-tubulin heterodimers and are the major constituents of mitotic spindles…
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