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barusiban

Known as: C4.6,S1-Cyclo(N-(3-sulfanylpropanoyl)-D-tryptophyl-L-isoleucyl-L-alloisoleucyl-L-asparaginyl-L-2-aminobutanoyl-N-methyl-L-ornithinol) 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Oligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Barusiban, a selective oxytocin receptor antagonist: placental transfer in rabbit, monkey, and human†
Abstract The use of drugs in pregnancy always raises concerns regarding potential fetal exposure and possible adverse effects… 
2014
2014
Late preterm birth is associated with short‐term morbidity but not with adverse neurodevelopmental and physical outcomes at 1 year
We compared the neonatal and infant outcomes at one year (Bayley mental and psychomotor development index, and physical growth… 
Review
2011
Review
2011
The Oxytocin-Oxytocin Receptor System and Its Antagonists as Tocolytic Agents
Oxytocin, a hormone involved in numerous physiologic processes, plays a central role in the mechanisms of parturition and… 
2009
2009
The effect of barusiban, a selective oxytocin antagonist, in threatened preterm labor at late gestational age: a randomized, double-blind, placebo-controlled trial.
2007
2007
Barusiban suppresses oxytocin-induced preterm labour in non-human primates
BackgroundPreterm labour (PTL) is a major cause of neonatal mortality and morbidity, and oxytocin (OT) antagonists are potential… 
2007
2007
Use of barusiban in a novel study design for evaluation of tocolytic agents in pregnant and neonatal monkeys, including behavioural and immunological endpoints.
2006
2006
Barusiban, An Effective Long-Term Treatment of Oxytocin-Induced Preterm Labor in Nonhuman Primates1
Abstract Preterm labor (PTL) affects up to 25% of human pregnancies in developing countries, but there are few therapeutic… 
2005
2005
Barusiban, a new highly potent and long-acting oxytocin antagonist: pharmacokinetic and pharmacodynamic comparison with atosiban in a cynomolgus monkey model of preterm labor.
Preterm labor (PTL) represents a significant unmet clinical need that affects up to 20% of all pregnancies and is a leading cause… 
2005
2005
Binding domains of the oxytocin receptor for the selective oxytocin receptor antagonist barusiban in comparison to the agonists oxytocin and carbetocin.
Highly Cited
2004
Highly Cited
2004
Inhibitory Effect of Barusiban and Atosiban on Oxytocin-Induced Contractions of Myometrium From Preterm and Term Pregnant Women
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