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azomycin

Known as: 2-nitroimidazole 
National Institutes of Health

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Broader (1)

Nitroimidazoles

Papers overview

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Review
2003
Review
2003
Non-invasive PET and SPECT imaging of tissue hypoxia using isotopically labeled 2-nitroimidazoles.
The measurement of pathologically low levels of tissue pO2 is an important diagnostic goal for determining the prognosis of many… 
Highly Cited
2000
Highly Cited
2000
BRU59-21, a second-generation 99mTc-labeled 2-nitroimidazole for imaging hypoxia in tumors.
UNLABELLED Hypoxia in tumors is believed to be an important cause of local failure of radiotherapy in certain types of cancer… 
Highly Cited
1996
Highly Cited
1996
In vitro and in vivo evaluation of a technetium-99m-labeled 2-nitroimidazole (BMS181321) as a marker of tumor hypoxia.
UNLABELLED The 99mTc-labeled 2-nitroimidazole derivative BMS181321, previously studied in experimental models of myocardial and… 
Highly Cited
1996
Highly Cited
1996
Measurement of hypoxia in human tumours by non-invasive spect imaging of iodoazomycin arabinoside.
Tumour oxygenation status in individual patients may be assessed using the bioreduction and linkage of 2-nitroimidazole markers… 
Highly Cited
1991
Highly Cited
1991
Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxia.
1-(5-Iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (IAZA) has been synthesised and labeled with 125I. Radioiodinated… 
1987
1987
DNA damage induced by reduced nitroimidazole drugs.
Highly Cited
1983
Highly Cited
1983
Studies on the action of nitroimidazole drugs. The products of nitroimidazole reduction.
Highly Cited
1982
Highly Cited
1982
Effect of specific chemotherapy on the levels of lytic antibodies in Chagas's disease.
Highly Cited
1978
Highly Cited
1978
Studies on the toxicity and radiosensitizing ability of misonidazole under conditions of prolonged incubation.
In vitro studies with CHO cells indicate that the 2-nitroimidazole, misonidazole, is markedly more toxic under hypoxic conditions… 
Highly Cited
1974
Highly Cited
1974
Radiosensitization of C3H Mouse Mammary Tumours by a 2-Nitroimidazole Drug
Local tumour control has been determined at 150 days after single doses of 240 kV x-rays given with or without 1 mg/g body weight… 
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