azomycin

Known as: 2-nitroimidazole 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
A glucose-responsive "closed-loop" insulin delivery system mimicking the function of pancreatic cells has tremendous potential to… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2012
Highly Cited
2012
TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard currently undergoing… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Hypoxia in solid tumors is associated with treatment resistance and increased metastatic potential. Although hypoxia has been… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
We investigated whether increasing levels of tissue hypoxia, measured by the binding of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Hypoxia is associated with tumor aggressiveness and is an important cause of resistance to radiation treatment. Assays of tumor… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Localization and quantitation of 2-nitroimidazole drug binding in low pO2 tumors is a technique that can allow the assessment of… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1997
Highly Cited
1997
PURPOSE To characterize the distribution of hypoxia and proliferation in human squamous cell carcinoma of the cervix via an… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Nitroimidazole markers of tumour hypoxia bind to normoxic liver and the question has been raised whether this is due to low… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The present studies were initiated to quantitate the oxygen dependence of bioreductive metabolism-induced binding of EF5, a… (More)
  • figure 1
  • figure 2
  • figure 5
  • figure 3
  • figure 6
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Hypoxic cells in tissue pose many medical problems, and there is a need for more accurate measurements of tissue hypoxia. However… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?