avermectins

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2018
0102019782018

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2013
2013
Avermectins are a family of macrolides known for their anthelmintic activities and traditionally believed to be inactive against… (More)
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2004
2004
The effect of a mixture of naturally occurring aversectin C and avermectin B(1) on the growth of ascites and solid experimental… (More)
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Highly Cited
2003
Highly Cited
2003
Species of the genus Streptomyces are of major pharmaceutical interest because they synthesize a variety of bioactive secondary… (More)
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2000
2000
Twenty-five avermectin analogs were assessed in a mouse seizure model. The ED(50) against pentylenetetrazole-induced tonic… (More)
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1997
1997
A subpopulation of CF-1 mice is unusual in its sensitivity to the avermectins, abamectin and ivermectin, with neurotoxicity… (More)
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1991
1991
Avermectins with a wide range of novel C-25 substituents have been prepared by feeding carboxylic acids or their biosynthetic… (More)
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1988
1988
The addition of glucose in the early stage of fermentation suppressed not only avermectin production but also the activity of 6… (More)
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1987
1987
A genetic recombination study of an industrial strain of Streptomyces avermitilis which produces avermectin is described. A… (More)
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Highly Cited
1979
Highly Cited
1979
The avermectins are a complex of chemically related agents which exhibit extraordinarily potent anthelmintic activity. They are… (More)
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1979
1979
When given to sheep as a single oral dose at 0.1 mg/kg, the B(1a) component of the avermectins caused a reduction of >95% in the… (More)
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